L-Menthol NEW
| Price | $8 | $5 | $0.8 |
| Package | 1KG | 25KG | 100KG |
| Min. Order: | 1KG |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2024-04-09 |
Product Details
| Product Name: L-Menthol | CAS No.: 2216-51-5 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2024/04/09 |
| Lead time: In stock, ready for shipment | In stock: bag/bottle/drum/IBC |
| COA, MSDS: Available, contact us for details | Origin: Manufacturer, advantage product |
| Deliver: By express, by air, by sea | NAME: Sun |
1. Materials information
| Name | (-)-menthol |
|---|---|
| Synonym | More Synonyms |
| Description | (-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i[1]. Antitumor activity[1]. |
|---|---|
| Related Catalog | Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cancer |
| Target | TRPM8[1] |
| In Vitro | (-)-Menthol (Menthol ) per se does not exhibit antiproliferative activity, but it is able to enhance 1α,25(OH)2D3-mediated growth inhibition in LNCaP cells. At high (-)-Menthol concentrations above 1.6 mM, the cells begin to detach from the culture dish[1]. (-)-Menthol (0.8 mM) can increase [Ca2+]i via transmembrane influx or store release pathways. Peak increase in [Ca2+]i was 102.3±39 nM (n=3) in (-)-Menthol alone and 124.5±51 nM (n=3) in combination of 1α,25(OH)2D3 with (-)-Menthol, respectively[1]. Combination of 1α,25(OH)2D3 with (-)-Menthol (0.8 mM) cooperatively modulates bcl-2 and p21 expression[1]. |
| References | [1]. Park EJ, et al. Menthol Enhances an Antiproliferative Activity of 1alpha,25-Dihydroxyvitamin D(3) in LNCaP Cells. J Clin Biochem Nutr. 2009 Mar;44(2):125-30. |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 215.4±8.0 °C at 760 mmHg |
| Melting Point | 41-43ºC |
| Molecular Formula | C10H20O |
| Molecular Weight | 156.265 |
| Flash Point | 93.3±0.0 °C |
| Exact Mass | 156.151413 |
| PSA | 20.23000 |
| LogP | 3.20 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.457 |
| Water Solubility | insoluble |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 8613526505137
Company Profile Introduction
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China
- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro