β-Nicotinamide Mononucleotide NEW

Chinese name: Β- nicotinamide mononucleotide

English name: beta-Nicotinamide Mononucleotide

CAS: 1094-61-7

Molecular formula: C11H15N2O8P

Molecular weight: 334.22

Melting point: 166 °C(dec.)

Storage conditions: 2-8°C

Solubility: Soluble in DMSO (slightly heated), methanol (slightly), water (slightly)

Form: solid

Color: White to yellow

Merck: 13,6697

BRN: 3570187

Stability: Very hygroscopic

InChI: InChI = 1 / C11H15N2O8P/c12-10 (16) of the 6-2-1-3-11-13 (4-6) 9 (15) 8 (14) 7 (21-11), 5-20-22 (17, 18) 19 / h1-4, 7-9,11,14-15 h, 5 h2, H3-12,16,17, 18th and 19th)/t7 has -, 8 -, 9-11 - / s3

InChIKey: DAYLJWODMCOQEW-TURQNECASA-N

SMILES: O @ @ H [C] 1 @ @ H [C] (@ @ H [C] (COP (O) ([O]) = O) O @ H [C] 1 / N + 1 = CC = CC (C = O N) = C1) O | & 1-1, 2,3,11, r |

character

The appearance of β-nicotinamide mononucleotide is white to yellowish, is a crystalline powder, and has no obvious odor.

use

In mammals, β-nicotinamide mononucleotides are generated by Nicotinamide (Nam) catalyzed by Nampt (a protease in vivo), followed by NAD+ catalyzed by nicotinamide mononucleotide adenosyltransferase. Nicotinamide mononucleotide is a direct way to supplement NAD+. Niacinamide mononucleotides can reverse aging by significantly improving the repair ability of DNA damage in cells