Product Details
| Product Name:
(+)-SHIN1 |
CAS No.:
2443966-90-1 |
| Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | (+)-SHIN1 |
| Description | (+)-SHIN1 ((+)-RZ-2994) is the active (+) enantiomer of SHIN1, which inhibits human serine hydroxymethyltransferase 1 and 2 (SHMT1/2). |
| In vitro | (+)-SHIN1 ((+)-RZ-2994) exhibits potent inhibition of cytosolic SHMT1, with IC50 values of less than 50 nM in SHMT2 deletion cells and 870 nM in HCT-116 cells, effectively blocking cell growth [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (249.71 mM)
|
| Keywords | (+)SHIN1 | SHIN1 | RZ-2994 | (+) SHIN1 | RZ2994 | RZ 2994 | SHIN 1 | (+)-SHIN-1 | SHIN-1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$71.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |
United States