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Postion:Product Catalog >API>Antineoplastic agents>MonoMethyl auristatin E
MonoMethyl auristatin E
  • MonoMethyl auristatin E
  • MonoMethyl auristatin E
  • MonoMethyl auristatin E
  • MonoMethyl auristatin E
  • MonoMethyl auristatin E

MonoMethyl auristatin E

Price $7
Package 1g
Min. Order: 1g
Supply Ability: 10 Kg
Update Time: 2020-11-16

Product Details

Product Name: MonoMethyl auristatin E CAS No.: 474645-27-7
Min. Order: 1g Purity: 99%
Supply Ability: 10 Kg Release date: 2020/11/16
MonoMethyl auristatin E Basic information
Product Name: MonoMethyl auristatin E
Synonyms: MonoMethyl auristatin E;MMAE;Vedotin;MonoMethyl auristatin E(MMAE, vedotin);HM-297C-22;MonoMethyl auristatin E (MMAE);N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide;N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide Monomethyl
CAS: 474645-27-7
MF: C39H67N5O7
MW: 717.97858
EINECS:  
Product Categories: intermediates
Mol File: 474645-27-7.mol
Article illustration
 
MonoMethyl auristatin E Chemical Properties
 
Safety Information
 
MSDS Information
 
 
MonoMethyl auristatin E Usage And Synthesis
Uses Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization. Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. MMAE is typically coupled to the antibody via a protease-cleavable linker, allowing separation of the drug from the antibody following intracellular localization.[Cayman Chemical]

Company Profile Introduction

Longyan Tianhua Biological Technology Co., Ltd is located in Longyan city, Fujian Province, China. It is a large-scale high-tech integrated enterprise dedicated to the research, development and sales of fine chemicals, pharmaceutical raw material intermediates, food and feed additives. The company has its own research and development base, equipped with advanced production equipment and efficient and precise testing instruments, has set up a strict and scientific quality management system, and constantly committed to technological innovation, product innovation and management innovation, so as to ensure that our products have super competitiveness in the same industry.? Company's main: Phenformin Hydrochloride, Chlorhexidine Acetate, Indomethacin Biphenyl benzyl azole dyclonine hydrochloride clorprenaline hydrochloride griseofulvin chloramphenicol maleic acid to guangxi pp qi, fucus xanthine tert-butyl of hydroxy anisole (BHA), ammonia, benzene pteridine zonisamide moxifloxacin mother nucleus moxifloxacin side chain moxifloxacin hydrochloride clobetasol propionate tranexamic acid raw material, and so on.? The annual sales volume of the company is around 3 million DOLLARS. Its products have been sold to more than 40 countries and regions all over the world, and have been well received. Moreover, the buyback rate of customers is very high. Longyan Tianhua Biotechnology Co., LTD. Is looking forward to long-term cooperation with you.

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