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Febuxostat
Price | $100 |
Package | 1KG |
Min. Order: | 1KG |
Supply Ability: | 999 |
Update Time: | 2020-11-16 |
Product Details
Product Name: Febuxostat | CAS No.: 144060-53-7 |
Min. Order: 1KG | Purity: 99 |
Supply Ability: 999 | Release date: 2020/11/16 |
Febuxostat Basic information |
Indications and Usage Mechanisms of Action |
Product Name: | Febuxostat |
Synonyms: | Febuxostat (Uloric);FBX;Uloric;Febuxostat (TEI-6720);Febuxostat Tablets;FEBUXOSTAT API;Febuxostat (This product is unavailable in the U.S.);Febuxostat Tabletshehe |
CAS: | 144060-53-7 |
MF: | C16H16N2O3S |
MW: | 316.37 |
EINECS: | 1308068-626-2 |
Product Categories: | zjh;API;Febuxostat;TRILIPIX;Other APIs;eterocycles;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 144060-53-7.mol |
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Febuxostat Chemical Properties |
Melting point | 238-239°(dec.) |
storage temp. | Refrigerator |
Merck | 14,3948 |
CAS DataBase Reference | 144060-53-7(CAS DataBase Reference) |
Safety Information |
RTECS | XJ3675310 |
MSDS Information |
Febuxostat Usage And Synthesis |
Indications and Usage | Febuxostat is a new generation xanthine oxidase inhibitor developed by Tejin Co. (Japan,) used clinically for for long-term treatment of hyperuicemia (gout,) a new and highly effective non-purine selective inhibitor of xanthine oxidase. It is not recommended for gout patients without hyperuricemia. |
Mechanisms of Action | The production of uric acid in the body is related to purine metabolism. In the last step of the production, hypoxanthine produces xanthine through the action of xanthine oxidoreductase (XOR), finally producing uric acid. Inhibiting the activity of this enzyme can effectively reduce the production of uric acid. Xanthine oxidase is the main enzyme promoting uric acid production. Through highly selective inhibition of oxidized and reduced xanthine oxidase, Febuxostat can reduce synthesis of uric acid, decreasing its concentration and effectively treating gout . Through liver metabolism, Xanthine oxidase does not rely on renal excretion, so patients with moderate to severe liver and kidney dysfunction do not need to reduce dosages. Febuxostat is a non-purine XOR inhibitor, so it is very safe. |
Chemical Properties | Crystalline Solid |
Uses | antihyperlipidemic |
Uses | Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. |
Uses | Febuxostat is primarily indicated in conditions like Gout, Hyperuricemia |
Company Profile Introduction
Longyan Tianhua Biological Technology Co., Ltd is located in Longyan city, Fujian Province, China. It is a large-scale high-tech integrated enterprise dedicated to the research, development and sales of fine chemicals, pharmaceutical raw material intermediates, food and feed additives.
The company has its own research and development base, equipped with advanced production equipment and efficient and precise testing instruments, has set up a strict and scientific quality management system, and constantly committed to technological innovation, product innovation and management innovation, so as to ensure that our products have super competitiveness in the same industry.?
Company's main: Phenformin Hydrochloride, Chlorhexidine Acetate, Indomethacin Biphenyl benzyl azole dyclonine hydrochloride clorprenaline hydrochloride griseofulvin chloramphenicol maleic acid to guangxi pp qi, fucus xanthine tert-butyl of hydroxy anisole (BHA), ammonia, benzene pteridine zonisamide moxifloxacin mother nucleus moxifloxacin side chain moxifloxacin hydrochloride clobetasol propionate tranexamic acid raw material, and so on.?
The annual sales volume of the company is around 3 million DOLLARS. Its products have been sold to more than 40 countries and regions all over the world, and have been well received. Moreover, the buyback rate of customers is very high.
Longyan Tianhua Biotechnology Co., LTD. Is looking forward to long-term cooperation with you.
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- Since: 2019-10-11
- Address: Room 201, 11 Xinhouying Road, Xicheng Lian, Xinluo District, Longyan City, Fujian Province, China
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