2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide

Price	$9.8	$8
Package	1KG	25KG

Product Details

Product Name: 2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide	CAS No.: 204205-90-3
Min. Order: 1KG	Purity: 95%~99.99%
Supply Ability: 10 MT/ Month	Release date: 2024/10/22
Delivery Time:: Fast	Transportation:: By sea， express， air，railway
Port:: Shanghai，Tianjin or Qingdao	Package:: Drum/ Bottle/ Bag/ IBC TANK
Name: Heidi 18

Heidi 18

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide Basic information

Product Name:	2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide
Synonyms:	2-[1-[(4-chlorophenyl)methyl]indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide;Nascapine;ZIO 301;2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide;Indibulin;2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide;lindiblin
CAS:	204205-90-3
MF:	C22H16ClN3O2
MW:	389.83
EINECS:
Product Categories:	Anticancer.
Mol File:	204205-90-3.mol

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide Chemical Properties

density	1.31±0.1 g/cm3(Predicted)
storage temp.	Desiccate at -20°C
pka	9.38±0.70(Predicted)

Safety Information

MSDS Information

2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide Usage And Synthesis

Biological Activity

Microtubule destabilizer that blocks tubulin polymerization (IC 50 = 0.3 μ M). Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC 50 values ranging from 0.036-0.285 μ M). Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo . Lacks neurotoxicity due to an ability to discriminate between posttranslationally modified tubulin in mature neuronal microtubules and less-modified tubulin present in immature neuronal or nonneuronal microtubules. Displays oral availability and efficacy towards MDR tumor cells.

Company Profile Introduction

Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).

Recommended supplier

Product name	Price		Suppliers	Update time
2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide	$1.10/1g	VIP4Y	Shaanxi Dideu Medichem Co. Ltd	2021-04-30
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide	$117.00/1mg	VIP5Y	TargetMol Chemicals Inc.	2024-10-31
[6-(4-Methylpiperazin-1-yl)pyridin-3-yl]boronic acid hydrochloride salt	$0.00/5mg	VIP3Y	TargetMol Chemicals Inc.	2024-10-28
4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic acid	$67.00/1kg	VIP3Y	Hebei Fengjia New Material Co., Ltd	2024-08-22

Product Details

Company Profile Introduction

You may like

Recommended supplier

Career Henan Chemica Co

Min. Order:	1KG
Supply Ability:	10 MT/ Month
Update Time:	2024-10-22