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Ketoconazole
Price | $20 |
Package | 1KG |
Min. Order: | 25KG |
Supply Ability: | 999 |
Update Time: | 2020-11-16 |
Product Details
Product Name: Ketoconazole | CAS No.: 65277-42-1 |
EC-No.: 265-667-4 | Min. Order: 25KG |
Purity: 99 | Supply Ability: 999 |
Release date: 2020/11/16 |
CAS: 65277-42-1
EINECS: 265-667-4
MF: C26H28Cl2N4O4
MW: 531.43
Assay: 99% min.
Standard: EP/BP/USP
Packing: 25Kg/cardboard drum
Character: White crystalline powder. Melting point 146 ºC, insoluble in water.
Usage: Imidazole antifungal agents. For the treatment of conditions such as athlete's foot and excessive dandruff.
Ketoconazole is an imidazole fungicidal agent with a very broad spectrum of activity against many fungal species that is used for treatment of superficial and systemic fungal infections. Ketoconazole is a well documented cause of clinically apparent acute drug induced liver injury and is no longer recommended as a first line antifungal agent.
Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor
Clinical application for treatment of hand eczema, athlete's foot, skin, ringworm, tinea, jock itch, thrush, tinea versicolor and cutaneous candidiasis.
COA:
Items |
Standard |
Results |
Characters |
White or almost white powder |
Qualified |
Identification |
Meets the requirements |
Qualified |
Melting range |
148°C ~ 152°C |
148.0~ 150.0°C |
Appearance of solution |
Meets the requirements |
Qualified |
Organic volatile impurities |
Meets USP30 |
Qualified |
Specific rotation |
-1° ~ +1° |
0° |
|
-0.10° ~ +0.10° |
|
Chromatographic purity |
Meets the requirements |
Qualified |
Heavy metals |
≤0.002% |
Qualified |
Loss on drying |
≤0.5% |
0.1% |
Residue on ignition |
≤0.1% |
0.05% |
Assay |
98.0% ~ 102.0% |
99.69% |
|
99.0%~101.0% |
|
CONCLUSION: |
USP30 |
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- Since: 2019-10-11
- Address: Room 201, 11 Xinhouying Road, Xicheng Lian, Xinluo District, Longyan City, Fujian Province, China