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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>AMPA and kainate receptors>Memantine Hydrochloride
Memantine Hydrochloride
  • Memantine Hydrochloride

Memantine Hydrochloride

Price $10
Package 1g
Min. Order: 100g
Supply Ability: 20ton
Update Time: 2021-11-15

Product Details

Product Name: Memantine Hydrochloride CAS No.: 41100-52-1
Min. Order: 100g Purity: 99%
Supply Ability: 20ton Release date: 2021/11/15

Chemical Name:Memantine hydrochloride
CAS No :41100-52-1
Molecular Weight:215.76
Properties:white crystalline powder.
melting point: 290-295deg C.
Specification: ≥98.5%(GC)
Packing:25kg/bag,Composite woven bag(plastic bag inside)or PE bag, or 25kg/carton.
Storage&Transportation:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Avoid to contact water or moisture during storage&transportation.
Usage:

Used in field of medicines,to make Memantine Hydrochloride Tablet,which  treat dementia of the alzheimer type etc.

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European. The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other.

 

Item

Specification

Result

Appearance

White crystalline power

Conforms

Loss on drying

 ≤1.0%

0.31%

PH

 4.5~6.5

 5.2

Residue on ignition

≤0.1%

 0.04%

Assay

98.0-102.0%

99.86%

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