Berberine hydrochloride

Product Name: Berberine hydrochloride

CAS: 633-65-8

MF: C20H18ClNO4

MW: 371.81

EINECS: 211-195-9

Melting point 204-206 °C (dec.)

storage temp. +2C to +8C

solubility methanol: soluble

form Yellow powder

Colour Index 75160

color Yellow powder

Uses

antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant

Uses

An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs.

Uses

An ingredient in some commercial eyewash products.