Polymyxin B sulfate
Price | $4062 |
Package | 1KG |
Min. Order: | 10g |
Supply Ability: | 1000KG |
Update Time: | 2021-11-02 |
Product Details
Product Name: Polymyxin B sulfate | CAS No.: 1405-20-5 |
Min. Order: 10g | Purity: 99% |
Supply Ability: 1000KG | Release date: 2021/11/02 |
Melting point | 217-220°C (dec.) |
storage temp. | 2-8°C |
solubility | H2O: 50 mg/mL |
form | powder |
pka | pKa 8.9 (Uncertain) |
color | colorless or slightly yellow |
PH | pH (10g/L, 25℃) : 4.5~7.0 |
optical activity | [α]/D 20/D (Rotation: -2.3 +/- 0.2 degrees) |
Water Solubility | Soluble in water at 50mg/ml/n |
Merck | 14,7573 |
CAS DataBase Reference | 1405-20-5(CAS DataBase Reference) |
EPA Substance Registry System | Polymixin B sulfate (1405-20-5) |
Uses | Biochemical studies. Polymyxin B is a kind of anti-Gram-negative poly-peptide antibiotics which can alter membrane structure allowing small molecules leakage and inhibit the growth of Gram-negative bacteria. It has bactericidal effect on Escherichia coli through binding to the lipid A portion of bacterial lipopolysaccharide. Mechanism of action: bind and interfere with the permeability o the cellular membrane. Anti-bacteria spectrum: gram negative bacteria. |
Chemical Properties | White Solid |
Uses | antibacterial |
Uses | Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixtu re of Polymyxin B1 and B2 sulfate. Biological potency (dry basis): >6000U/mg. |
Uses | Polymyxin B sulfate is used as topical antibiotic agent, often used in combination with neomycin; products include ointments, creams, eye, and ear drops. |
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- Since: 2018-09-06
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