Chlorpheniramine maleate
| Price | $40 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 10 tons |
| Update Time: | 2021-08-12 |
Product Details
| Product Name: Chlorpheniramine maleate | CAS No.: 113-92-8 |
| EC-No.: 204-037-5 | Min. Order: 1KG |
| Purity: 99 | Supply Ability: 10 tons |
| Release date: 2021/08/12 |
Product Name: | Chlorpheniramine maleate | Molecular weight: | 390.8606 |
Appearance: | White Crystals Powder | Molecular Formula | C20H23ClN2O4 |
CAS | 113-92-8 | Boiling point | 579.3°C at 760 mmHg |
| EINECS | 204-037-5 | Melting point | 130-135ºC |
| Flash point | 304.2°C | Water solubility | 1-5 g/100 mL at 21ºC |
| MOQ | 1KG | Shelf Life | 2 Years |
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
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