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Postion:Product Catalog >API>Antineoplastic agents>Natural sources of antineoplastic>Irinotecan
Irinotecan
  • Irinotecan
  • Irinotecan
  • Irinotecan
  • Irinotecan
  • Irinotecan

Irinotecan

Price $12
Package 1KG
Min. Order: 1KG
Supply Ability: 500MT/month
Update Time: 2023-03-27

Product Details

Product Name: Irinotecan CAS No.: 97682-44-5
EC-No.: 691-567-9 Min. Order: 1KG
Purity: 99.9% Supply Ability: 500MT/month
Release date: 2023/03/27

99% Bulk Irinotecan Hydrochloride Anticancer Irinotecan Powder


NameIrinotecan
CAS No.97682-44-5
EINECSN/A
MFC33H39ClN4O6
MW623.14
Storage temp.2-8°C
Purity99% min
UsageAntineoplastic agents; API
AppearanceLight Yellow Powder


Irinotecan is a semi-synthetic derivatives of camptothecin which can be specifically combined with the topoisomerase I. Topoisomerase I induced reversible single-strand breaks, so that double-stranded structure of DNA unwinded. Irinotecan and its active metabolite SN-38 with topoisomerase I-DNA complex binding, thereby preventing the fractured single-stranded nucleic acid to be connected. Existing research suggests that irinotecan cytotoxicity due to DNA synthesis process. Replicase and a topoisomerase I-DNA irinotecan (or SN-38) triple complex interactions, causing DNA double-strand breaks. Mammalian cells can not efficiently repair the DNA double-strand breaks.


Article illustration

Article illustration

Company Profile Introduction

Xingtai Xingjiu New Material Technology Co., Ltd. was founded in 2018 and it is located in Xingtai City, Hebei Province.Our company aims to be a leading materials science company with innovation, customer orientation, inclusiveness and sustainability, committed to the sustainable development of society through our expertise in materials science and deep collaboration with our customers. Xingjiu company produces industrial intermediates, cosmetics raw materials, solvents and other daily chemical raw materials, to provide customers with a wide range of technology based on differentiated products and right solutions.Our goal is to be a leading position on chemical industry.With vigorous and progressive spirit and strong competitive strength, our company will strive to provide customers with high quality industrial products and excellent service, in order to achieve the lofty goal. Xingjiu company adheres to four core values of customer first, team building, innovation and responsibility.If you are interested in our products, please contact us by emails or calls.We will get back to you in time. Look forward to our cooperation.

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  • Since: 2018-04-16
  • Address: Guangzong Economic Development Zone, Xingtai City, Hebei Province
INQUIRY
李秋燕
+86-17731987558
xingjiu@xingjiubiotech.com