GS-441524

Laboratory Production of GS-441524 to Treat FIP

Basic Information

GS-441524 structure	Common Name	GS-441524
	CAS Number	1191237-69-0	Molecular Weight	291.26
	Density	1.84±0.1 g	Boiling Point	N/A
	Molecular Formula	C12H13N5O4	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

How GS441 Cures FIP

If a cat's immune system is healthy and mature, the white blood cells should fight off an infection or virus, and allow the cat to build up an immune response, or antibodies.  Cats who develop FIP have an immune defect or deficiency that causes the white blood cells to replicate, rather than fight, the virus. Essentially, the cats immune system is spreading the virus throughout the cat's body rather than trying to eliminate it.  Cats who have no immune response develop wet FIP, while cats who have a partial immune response develop dry FIP. 
The nucleoside analog GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase.  In layman's terms, GS441 interjects itself into the chain reaction and stops the replication of the virus.  

Palliative Care For Cats With FIP
We understand that there are many reasons why someone may not want to use GS441.  While it is highly effective, it is also still experimental and in many circumstances, cost prohibitive. 
For those who wish to provide palliative treatment to their FIP cat, there are several options available. 

Polyprenyl Immunostimulant
Polyprenyl Immunostimulant, or "PI" as it is commonly referred to in the FIP groups, is an oral supplement that is administered daily for 1-2 weeks, then every other day once the jump-start dose is completed.  PI is approved to treat feline herpes; however, it is used off-label to treat feline infectious peritonitis.  It is not a cure of FIP, but there have been some long term FIP survivors.  PI is best suited for dry FIP, and the success rate (defined as surviving 1 year or more) is approximately 10%.  
Polyprenyl is used to enhance and strengthen the cat's immune system, ideally to allow the cat to fight off the virus. 
Cats who are using Polyprenyl should also be receiving overall systemic support by way of weekly B12 injections, daily B12 supplements, and if and as needed, appetite stimulants and ant-nausea medication.  Typically an anti-viral medication will also be prescribed for 10-14 days. 
PI must be prescribed and ordered by a veterinarian. The necessary forms and ordering information can be found on Vet Immune's website. 
*Cats who are taking Polyprenyl for FIP should NOT be taking steroids, as steroids will weaken the cat's immune system and work against the PI. 

Steroid Treatment for FIP
For many years, steroid treatment was the only option for FIP cats.  It is entirely palliative in nature, i.e. it's purpose is to keep the cat comfortable for however much time he/she has left.  
Steroids are inexpensive and can help provide temporary comfort to an FIP cat by increasing appetite, reducing fever, reducing inflammation, and with wet FIP, steroids may also help to reduce the effusion.

Home Care/Supportive Care
The success of palliative care, as well as your cat's quality of life, depends highly on supportive care and treating symptoms such as inappetence, fever, anemia, diarrhea and more.  Please continue reading about supportive care here. 

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Our Company

Shanghai Biolang Biological Co., Ltd has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.

Payment & Delivery

Why choose us?  

1. Products with high purity and good quality
2. Choose the most suitable price according to customer needs to achieve a win-win situation.
3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
4. Track the transportation of goods throughout the process
5. Safe raw materials from China
6. Have professional customs clearance capabilities and the best pre-sales and after-sales services.

our service
1. Cooperate with scientific research institutes and major factories to strictly control the entire process of products from raw materials to finished products
2. Customer first, we provide reasonable prices, high-quality products and timely delivery.
3. We can send the goods directly to your receiving address.
4. Quickly and accurately answer customers' doubts
5. If you place a large number of orders with us, we can provide preferential prices
6. Products can be packaged according to customer requirements.

FAQ

Q1: Can I get some samples?
Answer: Yes, we can provide free samples, but the freight is paid by our customers.

Q2: How to confirm the product quality before placing an order?
Answer: You can get samples of some products for free, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us your product specifications and requirements, and we will manufacture products according to your requirements.

Q3: How to start an order or payment?
After the order is confirmed, the PI will be sent first with our bank information. Payment via T/T, Western Union, Letter of Credit, Alibaba Trade Assurance, Cashapp, Moneygram or Bitcoin.

Q4: How to place an order?
You can contact me through Trademanager, WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and we will give you a quote. If you choose one of the above payment methods, we will arrange delivery for you.

Q5: Are there any discounts?
Answer: There are different discounts for different quantities.


Q6: How about your delivery time?
Answer: Generally speaking, it will take 3 to 5 days after receiving your prepayment. (Excluding Chinese holidays)

Q6: How do you deal with quality complaints?
Answer: First of all, our quality control will reduce quality problems to close to zero. If the quality problem is indeed caused by us, we will replace it for you free of charge or refund your loss.