![2'-Deoxyuridine](/ProductImageEN/2024-06/Large/3d191215-6239-4305-bff6-5b8cd7f044c0.png)
2'-Deoxyuridine
Price | $1990 |
Package | 1Kg |
Min. Order: | 1Kg |
Supply Ability: | 500 Kg |
Update Time: | 2024-06-22 |
Product Details
Product Name: 2'-Deoxyuridine | CAS No.: 951-78-0 |
Min. Order: 1Kg | Purity: 98 |
Supply Ability: 500 Kg | Release date: 2024/06/22 |
2'-Deoxyuridine |
2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.
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- Since: 2021-09-15
- Address: 425 Hespeler Rd, Cambridge, ON, Canada N1R 8J6