2,2-Dimethyl-1,3-dioxane-4,6-dione NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-08-23 |
Product Details
| Product Name: 2,2-Dimethyl-1,3-dioxane-4,6-dione | CAS No.: 2033-24-1 |
| EC-No.: 217-992-8 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/08/23 |
| CAS: | 2033-24-1 |
| MF: | C6H8O4 |
| MW: | 144.13 |
| EINECS: | 217-992-8 |
| Product Categories: | Drug Discovery;Dioxanes;Dioxanes & Dioxolanes;pharmaceutical intermediates;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;2033-24-1 |
| Mol File: | 2033-24-1.mol |
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| 2,2-Dimethyl-1,3-dioxane-4,6-dione Chemical Properties |
| Melting point | 92-96 °C(lit.) |
| Boiling point | 182.71°C (rough estimate) |
| density | 1.1311 (rough estimate) |
| vapor pressure | 0.044-133Pa at 25℃ |
| refractive index | 1.4434 (estimate) |
| storage temp. | 2-8°C |
| solubility | dioxane: soluble5%, clear to very slightly hazy, colorless to faintly yellow |
| pka | 5.1(at 25℃) |
| form | Crystals or Powder |
| color | Brownish-white to beige-brown |
| Water Solubility | 2.5 g/100 mL (20 ºC) |
| Merck | 14,5817 |
| BRN | 117310 |
| InChIKey | GXHFUVWIGNLZSC-UHFFFAOYSA-N |
| LogP | -1.58-4.786 at 25℃ |
| CAS DataBase Reference | 2033-24-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Dioxane-4,6-dione, 2,2-dimethyl-(2033-24-1) |
| EPA Substance Registry System | 1,3-Dioxane-4,6-dione, 2,2-dimethyl- (2033-24-1) |
| 2,2-Dimethyl-1,3-dioxane-4,6-dione Usage And Synthesis |
| Description | Meldrum's acid, also known as 2,2-dimethyl-1,3-dioxane-4,6-dione, is an organic compound with the formula C6H8O4. The compound was first made in 1908 by Andrew Norman Meldrum by a condensation reaction of malonic acid with acetone in acetic anhydride and sulfuric acid. Meldrum misidentified the structure as a β-lactone of β-hydroxyisopropylmalonic acid. Yet Meldrum's acid has a high acidity with a pKa of 4.97, because like ascorbic acid, deprotonation at the methylene next to the carbonyls produces a stable enolate. Because of this property Meldrum's acid like malonic acid is a reactant in Knoevenagel condensations. |
| Chemical Properties | The compound appears as white to beige crystals. It has a melting point of 94-95℃ (decomposition), is insoluble in water, and is soluble in ethanol and acetone. |
| Uses | Meldrum's acid serves as an intermediate in a variety of organic synthesis reactions. It is commonly used as an alternative to acyclic malonic esters and generally acts as a C3O2 synthon in organic synthesis. |
| Uses | An antimicrobial agent |
| Application | 2,2-Dimethyl-1,3-dioxane-4,6-dione was used in the synthesis of: macrocyclic β-keto lactone 4-pyridyl-substituted heterocycles 2-substituted indoles isofraxidin. |
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Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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Japan
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