3-Hydroxycinnamic acid NEW

3-Hydroxycinnamic acid, also known as m-coumaric acid or meta-hydroxycinnamic acid, is an organic compound belonging to the hydroxycinnamic acid family. It is one of the isomers of hydroxycinnamic acid, distinguished by the position of the hydroxyl group (-OH) on the benzene ring.

Chemical Structure and Properties

• Chemical Formula: C9H8O3

• Molecular Weight: 164.16 g/mol

• Structure: The chemical structure consists of a benzene ring with a hydroxyl group at the meta position (3rd position) relative to the propenoic acid side chain (-CH=CH-COOH).

• Appearance: It typically appears as a white or off-white crystalline powder.

• Solubility: Soluble in organic solvents such as ethanol and methanol; slightly soluble in water.

• Stability: Stable under normal conditions but should be stored in a cool, dry place, protected from light and moisture to prevent degradation.

Applications of 3-Hydroxycinnamic Acid

1. Antioxidant

• Application: Like other hydroxycinnamic acids, 3-hydroxycinnamic acid exhibits antioxidant properties, which help neutralize free radicals and protect cells from oxidative damage.

• Benefits:

• Food Industry: Can be used as a natural antioxidant in food products to extend shelf life and prevent oxidation.

• Cosmetics: Incorporated into skincare products for its protective effects against environmental stressors.

2. Pharmaceuticals and Nutraceuticals

• Application: Used in the development of drugs and dietary supplements for its potential health benefits.

• Benefits:

• Anti-inflammatory: Has shown potential anti-inflammatory effects, which may be beneficial in the treatment of various inflammatory conditions.

• Cardiovascular Health: May contribute to heart health by preventing oxidative stress and inflammation.

3. Precursor in Organic Synthesis

• Application: Employed as an intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.

• Benefits:

• Versatile Building Block: Its structure makes it a valuable starting material for creating more complex molecules in chemical synthesis.

4. Research and Development

• Application: Used in scientific research to study the properties and potential applications of hydroxycinnamic acids.

• Benefits:

• Biological Studies: Research into the biological effects of 3-hydroxycinnamic acid helps to understand its role in health and disease.

Safety and Handling

• Toxicity: 3-Hydroxycinnamic acid is generally considered to have low toxicity, but care should still be taken when handling it to avoid unnecessary exposure.

• Handling: Standard laboratory safety procedures should be followed, including wearing gloves, eye protection, and appropriate ventilation.

• Storage: Store in a tightly sealed container, in a cool, dry place, away from direct sunlight and moisture.

Summary

3-Hydroxycinnamic acid is a hydroxycinnamic acid isomer with valuable antioxidant, anti-inflammatory, and potential health-promoting properties. It finds applications in the food, pharmaceutical, and cosmetic industries, as well as in organic synthesis and scientific research. Its stability and relatively low toxicity make it a useful compound for various industrial and research purposes.

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