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Postion:Product Catalog >API>Hormones and the Endocrine System>Adrenal corticosteroids>Clobetasol propionate
Clobetasol propionate
  • Clobetasol propionate

Clobetasol propionate

Price $100
Package 1KG
Min. Order: 10G
Supply Ability: 100kg/week
Update Time: 2019-01-15

Product Details

Product Name: Clobetasol propionate CAS No.: 25122-46-7
EC-No.: 246-634-3 Min. Order: 10G
Purity: 99%min Supply Ability: 100kg/week
Release date: 2019/01/15

Pharmaceutical Raw Materials Clobetasol Propionate CAS 25122-46-7 For Inflammatory Treatment Skin Disorders

 

Abstract

 

Clobetasol propionate is part of a group of drugs known as glucocorticoids, which are a type of corticosteroid (or "steroid" for short). Although glucocorticoids have numerous effects in the body, they are used mostly for their anti-inflammatory or immune-suppressing properties. Clobetasol propionate works for most conditions by decreasing inflammation or suppressing an overactive immune system.


Clobetasol propionate is a corticosteroid of synthetic steroid used to treat various skin disorders including inflammation, itching, herpes labialis, eczema, psoriasis and lichen sclerosus.

Clobetasol propionate is also highly effective for contact dermatitis caused by exposure to poison ivy/oak and auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).

Clobetasol propionate is used as first-line treatment for both acute and chronic GVHD of the skin.

 

Specification

 

Product name Clobetasol propionate
CAS No. 25122-46-7 Outer Packing 1KG/bag
Production date 2016.05 Shelf life 2021.04
Test Observation Limit
Description White crystalline powder White to cream crystalline powder
Solubility Complies As per USP
Identification Complies As per USP
Melting range 196ºC About 196ºC
Specific optical Rotation(on dried basis) +100.92° +98° to +104°
Loss on drying 0.25% Not more than 2.0%
Residue on ignition 0.06% Not more than 0.1%
Heavy Metals Complies Not more than 20 ug/gm
Chromatographic purity
i)Any individual impurity
Ii)Total impurity
0.36%
0.58%
Not more than1.0%
Not more than2.5%
Assay(on dried basis) 99.4% Not less than97.0%&Not more than102.0%
Residualsolvents
Methylene chloride
Acetone
Ethyl Acetate
Methanol

DMF
N.D.
N.D.
N.D.
928.86ppm
N.D.
N.D.
Not more than 600 ppm
Not more than 5000 ppm
Not more than 5000 ppm
Not more than 3000 ppm
Not more than200 ppm
Not more than 880 ppm

Application

Adrenal corticosteroids and adrenocorticotropic hormone drugsClobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,[4] psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.

 

Usage


1. For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe
corticosteroid-responsive dermatoses of the scalp.


2. Topical corticosteroid. Glucocorticoid; anti-inflammatory

Company Profile Introduction

Hubei XinRunde Chemical Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia,and so on.

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