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Postion:Product Catalog >API>Hormones and the Endocrine System>Adrenal corticosteroids>Fluticasone propionate
Fluticasone propionate
  • Fluticasone propionate

Fluticasone propionate

Price $100
Package 1KG
Min. Order: 10G
Supply Ability: 100kg/week
Update Time: 2019-01-15

Product Details

Product Name: Fluticasone propionate CAS No.: 80474-14-2
Min. Order: 10G Purity: 99.9%
Supply Ability: 100kg/week Release date: 2019/01/15

99% Pharmaceutical Raw Materials Corticosteroids Powder Fluticasone Propionate CAS 80474-14-2

 

Fluticasone Propionate Details:

 

Products name Fluticasone propionate
MW 500.57
MF C25H31F3O5S
CAS 80474-14-2
Appearance White powder
Purity 99%
Usage An antiallergic; anti-asthmatic; anti-inflammatory.
Category Corticosteroids

 

Fluticasone Propionate Description:

 

Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein. It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis.

 

Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen, estrogen, or mineralocorticoid receptor thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (e. G. Mast cell, eosinophil, neutrophil, macrophages, and lymphocytes) and mediators (e. G. Histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability.

 

Fluticasone Propionate Usage:

 

(1) Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation.
(2) Fluticasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. Fluticasone nasal is for use in adults and children who are at least 2 years old.
(3) Fluticasone is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis

 

Fluticasone Propionate COA

 

Items of analysis Specification Results
Appearance white or almost white powder Conform
Identification IR & HPLC Conform
Solubility Practically insoluble in water Conform
Specific Rotation +32-+36° Conform
Water 0.2% max 0.15%
Chromatographic Purity ≥99.0% 99.54%
Impurity A 0.2%max. Conform
Impurity B,C 0.1%max Conform
Impurity D,E 0.3%max. Conform
Any other impurity 0.1%max. Conform
Acetone Not more than 1.0% Conform
DMF NMT 880 PPM Conform
THF NMT 720 PPM Conform
PYRIDINE NMT 200 PPM Conform
METHANOL NMT 3000 PPM Conform
N,N-DIMETHYLACETAMIDE NMT 1090 PPM Conform
Assay (by HPLC) 97.0% to 102.0% 99.50%
Conclusion Qualified
 

Company Profile Introduction

Hubei XinRunde Chemical Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia,and so on.

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