4-formyl-3-methoxybenzonitrile

‌Product Name‌: 4-Formyl-3-methoxybenzonitrile
‌CAS No.‌: 21962-45-8
‌Molecular Formula‌: C₉H₇NO₂
‌Molecular Weight‌: 161.16

🌟 ‌Product Overview‌

‌Brief Introduction‌: 4-Formyl-3-methoxybenzonitrile is a high-purity organic compound widely recognized as a critical intermediate in pharmaceutical synthesis, particularly for non-steroidal mineralocorticoid receptor antagonists like ‌Finerenone‌‌34. Its unique structure combines aldehyde and nitrile groups, enabling versatile reactivity in complex organic reactions‌18.
‌Primary Function‌: Key intermediate for ‌Finerenone‌ production and custom synthesis of aromatic compounds‌45.
‌Applicable Fields‌: Pharmaceutical manufacturing, fine chemical synthesis, and preclinical drug development‌45.

✅ ‌Key Advantages‌

🟡 ‌≥98% Purity‌: Rigorously tested via HPLC, NMR, and GC for precision‌14.
🟡 ‌Stable Storage‌: Maintains integrity under inert gas (N₂/Ar) at 2-8°C‌12.
🟡 ‌Scalable Supply‌: Available in 1g to 25kg packaging with bulk order support‌45.

📌 ‌Application Scenarios‌

1. ‌Finerenone Synthesis‌: Core intermediate for non-steroidal antihypertensive drugs‌45.

2. ‌Organic Synthesis‌: Building block for nitrile- and aldehyde-functionalized aromatic compounds‌14.

3. ‌API Development‌: Used in preclinical studies and optimization of novel drug candidates‌36.

🔬 ‌Quality Certifications‌

• ‌Testing Standards‌: Complies with USP/EP guidelines; validated by HPLC (>98%), NMR, and GC‌14.

• ‌Physical Properties‌: Melting point 109-111°C, boiling point 318°C, and flash point 138°C‌25.

📈 ‌Market Trends‌

The global demand for 4-Formyl-3-methoxybenzonitrile is surging due to its pivotal role in ‌Finerenone‌ production, a blockbuster drug for chronic kidney disease and heart failure. With increasing R&D investments in precision medicine, this intermediate is projected to witness ‌12% CAGR growth‌ by 2030, especially in Asia-Pacific markets‌45.