AZD6482 (S-isomer)

Price	$100
Package	1KG

Product Details

Product Name: AZD6482 (S-isomer)	CAS No.: 1173900-37-2
Min. Order: 10KG	Purity: 99
Supply Ability: 100kg	Release date: 2019/01/15

Chemical Information

Product Name	AZD6482 (S-isomer)
Iupac Chemical Name	(S)-2-((1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl)amino)benzoic acid
Synonyms	AZD6482 (S); AZD6482; AZD-6482; AZD 6482
Molecular Formula	C22H24N4O4
Molecular Weight	408.458
Smile	CC=1C=C(C=2N(C(C=C(N2)N2CCOCC2)=O)C1)[C@H](C)NC1=C(C(=O)O)C=CC=C1
InChiKey	IRTDIKMSKMREGO-HNNXBMFYSA-N
InChi	InChI=1S/C22H24N4O4/c1-14-11-17(15(2)23-18-6-4-3-5-16(18)22(28)29)21-24-19(12-20(27)26(21)13-14)25-7-9-30-10-8-25/h3-6,11-13,15,23H,7-10H2,1-2H3,(H,28,29)/t15-/m0/s1
Cas	1173900-37-2

Technical Data

Appearance	crystalline solid
Purity	98%
Solubility	Soluble in DMSO
Storage	3 years -20ºCpowder
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical.
Quality control

Description

AZD6482 is a potent, selective and ATP competitive PI3K inhibitor (IC(50) 0.01 μm). AZD6482 inhibited insulin-induced human adipocyte glucose uptake in vitro (IC(50) of 4.4 μm). This is the first human target validation for PI3K inhibition as anti-platelet therapy showing a mild and generalized antiplatelet effect attenuating but not completely inhibiting multiple signaling pathways with an impressive separation towards primary hemostasis. AZD6482 at 'supratherapeutic' plasma concentrations may attenuate insulin signaling, most likely through PI3K inhibition.

Company Profile Introduction

Hubei XinRunde Chemical Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia,and so on.

Recommended supplier

Product name	Price		Suppliers	Update time
AZD6482 (S-isomer)	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-06-27
trans ISRIB	$100.00/1box	VIP4Y	Wuhan Nutra Biotechnology Co.,Ltd	2022-06-21
Cefaclor Impurity G Isomer A	$0.00/10mg		Guangzhou PI PI BIOTECH INC	2022-04-23
5-Norbornene-2,3-dimethanol (mixture of endo-and exo-, predominantly endo-isomer)	$0.00/500g	VIP4Y	Henan Research New Materials Co., Ltd.	2021-12-11