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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>STAUROSPORINE
STAUROSPORINE
  • STAUROSPORINE

STAUROSPORINE

Price $1
Package 1KG
Min. Order: 1KG
Supply Ability: 1T
Update Time: 2019-07-06

Product Details

Product Name: STAUROSPORINE CAS No.: 62996-74-1
Min. Order: 1KG Purity: 98%
Supply Ability: 1T Release date: 2019/07/06

CR363 

Product Name: STAUROSPORINE
Synonyms: STSP;ANTIBIOTIC M 193;ANTIBIOTIC AM-2282;[9S-(9A,10B,11B,13A)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-1M]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE;2,3,10,11,12,13-HEXAHYDRO-10R-METHOXY-9S-METHYL-11R-METHYLAMINO-9S,13R-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1 ONE;STAUROSPORINE FROM STREPTOMYCES SP.;STAUROSPORINE READY-MADE SOLUTION;STAUROSPORINE FROM STREPTOMYCES SP., PGE WITH 250 UG
CAS: 62996-74-1
MF: C28H26N4O3
MW: 466.53
EINECS:  
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Protein Kinase;Signalling;Inhibitor;antibiotic;API
Mol File: 62996-74-1.mol
Article illustration
 
STAUROSPORINE Chemical Properties
Melting point  270°C
alpha  D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol)
RTECS  KD5084000
storage temp.  2-8°C
solubility  DMSO: soluble
Water Solubility  Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.
InChIKey HKSZLNNOFSGOKW-WIFUGMKFSA-N
 
Safety Information
Hazard Codes  Xn,T,Xi
Risk Statements  40-45-36/37/38-46
Safety Statements  36/37-53-36-26-45
RIDADR  UN 2811 6.1 / PGII
WGK Germany  2
8-10
HazardClass  3
HS Code  29419090
MSDS Information
Provider Language
SigmaAldrich English
 
STAUROSPORINE Usage And Synthesis
Chemical Properties Light Yellow Solid
Uses Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumour active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta.
Uses Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumor active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta.
Uses A protein Kinase C inhibitor that induces apoptosis in many cell types
Biological Activity Broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC 50 = 3 nM), protein kinase A (IC 50 = 7 nM), p 60v-src tyrosine protein kinase (IC 50 = 6 nM) and CaM kinase II (IC 50 = 20 nM). Also available as part of the Mixed Kinase Inhibitor Tocriset™ .

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Since: 2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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