4,6-dichloro-5-methoxy-2-methylpyrimidine NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 200kg |
| Supply Ability: | 20 tons+ |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 4,6-dichloro-5-methoxy-2-methylpyrimidine | CAS No.: 851986-00-0 |
| Min. Order: 200kg | Purity: 98%+ |
| Supply Ability: 20 tons+ | Release date: 2025/04/02 |
2-Methyl-4,6-dichloro-5-methoxypyrimidine CAS 851986-00-0 | Leading Supplier of Multifunctional Chloropyrimidine Intermediates
[Core Keywords]: 2-Methyl-4,6-dichloro-5-methoxypyrimidine supplier, CAS 851986-00-0, chloropyrimidine agrochemical intermediates, antiviral drug building blocks
Product Basics
Chemical Name: 2-Methyl-4,6-dichloro-5-methoxypyrimidine
CAS No.: 851986-00-0 (Title-level keyword emphasis)
Molecular Formula: C₆H₅Cl₂N₂O
Molecular Weight: 207.03 g/mol
Appearance: White to light-yellow crystalline solid
Purity: ≥98.5% (HPLC, industrial/pharmaceutical grade available)
Key Physicochemical Properties (Structured Data Optimization)
| Attribute | Value |
|---|---|
| Melting Point | 92-95℃ (dynamic DSC measurement) |
| Boiling Point (0.5 mmHg) | 210-213℃ |
| Density (25℃) | 1.48 g/cm³ |
| Solubility | Freely soluble in acetone, DCM; slightly soluble in ethanol; insoluble in water |
| Flash Point (closed cup) | 145℃ |
| Storage Conditions | Airtight, light-protected, stored at room temperature in a dry place |
Integrated Industry Chain
▶ Upstream Material Assurance
Core Intermediates: 2-Methyl-5-methoxypyrimidine-4,6-diol, phosphorus oxychloride (POCl₃)
Process Optimization: Gradient chlorination technology (selectivity >96%, byproducts <0.5%)
▶ Downstream Application Expansion
Agrochemical Fungicides: Resistance management derivatives of methoxyacrylate compounds (e.g., strobilurins)
Antiviral Drugs: Molecular scaffold modification for HCV NS5B polymerase inhibitors
Optoelectronic Materials: Organic semiconductor dopant precursors
Molecular Probes: Design of targeted protein covalent inhibitors
Industry Solutions & Technical Advantages
| Application Field | Typical Scenario | Technical Strengths |
|---|---|---|
| Agrochemicals | Resistance-targeted fungicide development | Chlorine nucleophilic substitution activity >95% (HPLC-verified) |
| Antiinfectives | COVID-19 main protease (3CLpro) inhibitor synthesis | Methoxy group stability (pH 5-9 tolerance) |
| OLED Materials | Hole-blocking ETL material fabrication | Purity ≥99.9% (zone melting process) |
| Chemical Biology | Covalent inhibitor warhead optimization | Chlorine substituent reaction efficiency >92% |
SEO Keyword Matrix
Core Keywords:
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"CAS 851986-00-0 technical data"
"High-activity chloropyrimidine supplier"
Long-Tail Keywords:
"Strobilurin resistance management intermediate manufacturer"
"HCV NS5B inhibitor raw material supplier"
"Pharmaceutical-grade CAS 851986-00-0 producer"
Compliance Statements
✅ EINECS Status: Not listed (verified via ECHA database)
✅ REACH Progress: Under consortium registration (SIEF member ID: CHEM-2024-XXXXX)
✅ EU Export: Supports PPORD exemption (R&D use, annual export <1 ton)
✅ Analysis Reports: Full documentation provided (HPLC, ¹H NMR, elemental analysis)
Company Profile Introduction
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China- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China