Desloratadine

Price	$1
Package	1KG

Product Details

Product Name: Desloratadine	CAS No.: 100643-71-8
Min. Order: 1G	Purity: 98%
Supply Ability: 100KG	Release date: 2019/07/06

AD68

Desloratadine Basic information

Product Name:	Desloratadine
Synonyms:	DESLORATADINE;DESLORATIDINE;8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridine;8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDINYLIDENE)-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE;AKOS 92131;SCH-34117;Aerius;Dis-loratadine
CAS:	100643-71-8
MF:	C19H19ClN2
MW:	310.82
EINECS:	1308068-626-2
Product Categories:	Active Pharmaceutical Ingredients;Antihistaminic;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals;Heterocycles;Metabolites & Impurities;API;FLUVENT;Other APIs;Inhibitors
Mol File:	100643-71-8.mol

Desloratadine Chemical Properties

Melting point	150-151°C
storage temp.	2-8°C
solubility	DMSO: >10mg/mL
Merck	14,2922
CAS DataBase Reference	100643-71-8(CAS DataBase Reference)

Safety Information

RTECS

DE8011000

MSDS Information

Desloratadine Usage And Synthesis

Description	Desloratadine is a second generation of tricyclic antihistamine. It is a H1-receptor antagonist which has anti-inflammatory activity. Its affinity to the H1 receptor is higher than most other H1-receptor antagonists. Desloratadine works by blocking a certain natural substance (histamine) which is produced during an allergic reaction. Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. Desloratadine is used to treat nasal and non-nasal symptoms (watery eyes, runny nose, itching eyes/nose, sneezing, and itching) of seasonal allergic rhinitis. It is also used to relieve chronic itching caused by hives.
Chemical Properties	Beige Solid
Uses	A histamine H1-receptor antagonist. An active metabolite of Loratadine
Uses	Nonsedating-type histamine H1-receptor antagonist. An active metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells.
Uses	antiinflammatory
Uses	For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.
Definition	ChEBI: Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis nd chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

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Product Details

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