Product Details
| Product Name:
Z-VAD-FMK |
CAS No.:
187389-52-2 |
| Min. Order:
1G |
Purity:
98% |
| Supply Ability:
100KG |
Release date:
2019/07/06 |
AD68
| Z-VAD-FMK Basic information |
| Product Name: |
Z-VAD-FMK |
| Synonyms: |
Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;Z-VAD(OME)-FMK |
| CAS: |
187389-52-2 |
| MF: |
C21H28FN3O7 |
| MW: |
453.46 |
| EINECS: |
|
| Product Categories: |
Caspases/Apoptosis;Caspase/Related Products;Apoptosis;peptides;API;Inhibitors |
| Mol File: |
Mol File |
 |
| |
| Z-VAD-FMK Chemical Properties |
| density |
1.214±0.06 g/cm3 (20 ºC 760 Torr) |
| Fp |
396.7℃ |
| storage temp. |
−20°C |
| solubility |
DMSO: 20 mg/mL |
| form |
powder |
| color |
white |
| InChIKey |
MIFGOLAMNLSLGH-QOKNQOGYSA-N |
| Safety Statements |
22-24/25 |
| WGK Germany |
3 |
| Provider |
Language |
| SigmaAldrich |
English |
| |
| Z-VAD-FMK Usage And Synthesis |
| Uses |
Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.[Cayman Chemical] |
| Biological Activity |
Cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC 50 = 0.0015-5.8 mM). Active in vivo . |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
You may like
-
CAS:915019-65-7
$1.00 / 1KG
-
CAS: 13349-82-1
$7.00 / 1KG
-
CAS: 1392136-43-4
$1.00 / 1KG
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$0.00/1KG |
VIP2Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-10-08 |
China