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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Stem Cells & Wnt>Hedgehog / Smoothened antagonist>NVP-LDE225
NVP-LDE225
  • NVP-LDE225
  • NVP-LDE225

NVP-LDE225

Price $2
Package 1kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2019-07-06

Product Details

Product Name: NVP-LDE225 CAS No.: 956697-53-3
Min. Order: 1kg Purity: 99%
Supply Ability: 100kg Release date: 2019/07/06
Product NUmber: : WM.560
NVP-LDE225 Basic information
Product Name: NVP-LDE225
Synonyms: NVP-LDE225;LDE225;Erismodegib;rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide;LDE225 (NVP-LDE225);[1,1'-Biphenyl]-3-carboxaMide, N-[6-[(2R,6S)-2,6-diMethyl-4-Morpholinyl]-3-pyridinyl]-2-Methyl-4'-(trifluoroMethoxy)-, rel-;NVP-LDE225(LDE225,ErisModegib);LDE225 (NVP-LDE225,ErisModegib)
CAS: 956697-53-3
MF: C26H26F3N3O3
MW: 485.4981496
EINECS: 1312995-182-4
Product Categories: Aromatics;Chiral Reagents;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 956697-53-3.mol
Article illustration
 
NVP-LDE225 Chemical Properties
density  1.255
 
Safety Information
MSDS Information
 
 
NVP-LDE225 Usage And Synthesis
Uses A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic.
Definition ChEBI: A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as it phosphate salt) for treatment of locally advanced basal cell carcinoma.
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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