Flumequine

Price	$1
Package	1kg

Product Details

Product Name: Flumequine	CAS No.: 42835-25-6
Min. Order: 1g	Purity: 99%
Supply Ability: 100KG	Release date: 2019/07/06
Product:: AD68

Flumequine Basic information

Animal-specific antibacterial drugs Uses

Product Name:	Flumequine
Synonyms:	9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid;FLUMEQUIN;FLUMEQUINE;Fluoromethylquinoline;Flumequine solution;FLUMEQUINE STANDARD SOLUTION;FLUMEQUINE PESTANAL, 250 MG;Fluoromethyl
CAS:	42835-25-6
MF:	C14H12FNO3
MW:	261.25
EINECS:	255-962-6
Product Categories:	Aromatics Compounds;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Quinolones and Fluoroquinolones;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Inhibits an EnzymeAntibiotics;Interferes with DNA SynthesisAntibiotics;Mechanism of Action;Spectrum of Activity;API's;Pharmaceutical raw material;FLUGERAL
Mol File:	42835-25-6.mol

Flumequine Chemical Properties

Melting point	253-255°C
RTECS	DK1672000
Fp	>110°(230°F)
storage temp.	0-6°C
solubility	1 M NH4OH: soluble50mg/mL
pka	pKa 6.42(H2O t=25.0 I=0.025)(Approximate)
color	white to off-white
Water Solubility	Soluble in DMSO and dilute alkali hydroxides. Insoluble in water
Merck	14,4137
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	42835-25-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-36/37/39-27-26
WGK Germany	3
F	10
HS Code	29339900
Hazardous Substances Data	42835-25-6(Hazardous Substances Data)

MSDS Information

Provider	Language
9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid	English
SigmaAldrich	English

Flumequine Usage And Synthesis

Animal-specific antibacterial drugs	It appears as white powder and is odorless and tasteless. It is insoluble in water but is immiscible with organic solvent. Flumequine is a kind of synthetic second-generation, animal-specific quinolone antibacterial drugs. It is currently the only non-humans shared broad-spectrum antimicrobial veterinary drug. It is taken as the substitute product of norfloxacin. It has a strong bactericidal activity with excellent efficacy in the treatment of animal bacterial diseases. Its main effect is to inhibit bacterial deoxy nucleic acid (DNA) gyrase, interfering with the deoxyribonucleic acid (DNA) synthesis, thereby causing failure of cell for further division, and thus playing the role of killing bacteria. It is mainly used in animal bacterial respiratory disease including E. coli, dysentery, salmonellosis, typhoid, fowl cholera, staphylococcal disease and infectious rhinitis. It can also be used for the treatment of E. coli disease, monospora disease and Vibrio disease in aquatic animals with strong inhibitory effect on the Aeromonas hydrophila. Flumequine was first successfully developed by the Rinker laboratory and had been successively and widely used in the EU and Japan and other countries in livestock and aquaculture since 1970s with excellent efficacy in the treatment of various kinds of diseases caused by Gram-negative infections, especially for the treatment of livestock, poultry and aquatic animal diseases caused by Escherichia coli, mycoplasma, and Aeromonas hydrophila. It had been gradually developed and approved to enter into market by our country in the late 1990s and mainly used for the control of bacterial infection diseases of salmon, trout, shrimp, eel and pigs as well as chickens. Since quinolones-class sodium flumequine can inhibit bacterial DNA gyrase and has a broad spectrum antibiotic, high efficiency, low toxicity and strong tissue penetration capability with no anesthesia effect, it has become one of the most important anti-infective drugs in veterinary clinical diagnosis and aquaculture and has been used extensively for the treatment, prevention and promoting growth. Because of its resistance and potential carcinogenicity, the European Union, Japan and China have all provided their maximal residue limit in the tissue (our country and the European Union both use the value of 100ppb). The current methods of detecting flumequine mainly include fluorescent spectrophotometry, enzyme-linked assay (ELISA) and liquid chromatography. ELISA, with its high sensitivity and easy operation, has become routine screening methods. This information is edited by Xiongfeng Dai from Chemicalbook.
Uses	It is a kind of newly synthetic broad-spectrum antimicrobial drugs with excellent efficacy in the treatment of animal bacterial diseases. It can be used as pharmaceutical raw material.
Chemical Properties	White Crystalline Solid
Uses	vasodilator
Uses	Fluorinated quinolone antibacterial

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

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career henan chemical co