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Postion:Product Catalog >API>Antipyretic analgesics>Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)>Flunixin meglumin in stock GMP Factory
Flunixin meglumin  in stock  GMP Factory
  • Flunixin meglumin  in stock  GMP Factory

Flunixin meglumin in stock GMP Factory

Price $1
Package 1KG
Min. Order: 1KG
Supply Ability: 1000 metric tons
Update Time: 2020-06-02

Product Details

Product Name: Flunixin meglumin in stock GMP Factory CAS No.: 42461-84-7
Min. Order: 1KG Purity: USP37/ EP8 /BPV 2012
Supply Ability: 1000 metric tons Release date: 2020/06/02
Contact person: Ms Ella Su - Manager E-mail: chemwill_asia@126.com;chemwill@hotmail.com
Website: www.chemwill.com
Website: http://www.chemwill.com

 

PLS contact  Ms Ella Lee  -   Deputy Sales Manager 

Phone: +86 -21-51086038
 
Email: chemwill_asia@126.com;chemwill@hotmail.com
 
  • ProName: Flunixin meglumin
  • CasNo: 42461-84-7
  • Molecular Formula: C14H11F3N2O2
  • Appearance: White crystalline powder
  • Application: Veteinary pharmaceutical
  • DeliveryTime: 10days
  • PackAge: 25kg 10kg,5kgs
  • Port: Chinese main port
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: 98%
  • Storage: Dry and cool condition
  • Transportation: By air by sea or express
  • LimitNum: 1 Kilogram
  • Related Substances: 98%
  • Residue on Ignition: 0.3%
  • Heavy Metal: 0.3%

Package: 25.0kg net drum

 

main uses: mammalian anti-inflammatory analgesia, can alleviate muscle abnormalities caused by inflammation and pain, treatment of diarrhea, tremor, colitis, respiratory diseases, endotoxin-induced mastitis, arthritis, fever, diarrhea, tremor, eye infections, etc.           

 

Product Name: Flunixin Meglumine
Chemical Name: 1-deoxy-1-(methylamino)-d-glucitol 2-[2-methyl-3-(perfluoromethyl)anilino]nicotinate

Cas No.: 42461-84-7

Molecular Formula: C21H28F3N3O7
Molecular Weight:  491.46 

 

flunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. it is a potent inhibitor of the enzyme cyclooxygenase. it has demonstrated biological activity in the following areas:

  • analgesia (loss of pain). flunixin meglumine demonstrated potent analgesic activity in laboratory studies with mice, rats, and monkeys. parenterally, flunixin meglumine showed anti-writhing activity in mice equal to pentazocine and was more potent than meperidine and codeine. in the rat yeast paw test, it was significantly more potent than pentazocine, meperidine, and codeine. in monkeys, flunixin meglumine produced analgesia comparable to a clinically effective dose of morphine. in the horse, it has been shown to be an effective treatment of pain associated with colic. in contrast to narcotic agents, its analgesic effects were not antagonized by naloxone, tolerance did not develop, and cross-tolerance to codeine did not occur. these results show that flunixin meglumine is an effective analgesic in animals, and drug dependence liability does not occur.
  • anti-inflammatory. flunixin meglumine showed anti-inflammatory activity in laboratory animals. a dose-related reduction in edema was recorded four hours after treatment. in the horse, anti-inflammatory activity was demonstrated in lameness models, showing relief of pain by improving stride length and reducing swelling.
  • potency. based on manufacturers' recommendations in the horse, parenteral banamine (flunixin meglumine), on a milligram per milligram basis, is four times as potent as phenylbutazone and twice as potent as ketoprofen. 

 

 

 

product name:  flunixin meglumine   

chemical name:  2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt

formula/structure: c14h11f3n2o2.c7h17no5         

molecular weight: 491.46        

cas no.: 42461-84-7

flunixin meglumine ;flunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. it is a potent inhibitor of the enzyme cyclooxygenase. it has demonstrated biological activity in the following areas:

 

  • analgesia (loss of pain). flunixin meglumine demonstrated potent analgesic activity in laboratory studies with mice, rats, and monkeys. parenterally, flunixin meglumine showed anti-writhing activity in mice equal to pentazocine and was more potent than meperidine and codeine. in the rat yeast paw test, it was significantly more potent than pentazocine, meperidine, and codeine. in monkeys, flunixin meglumine produced analgesia comparable to a clinically effective dose of morphine. in the horse, it has been shown to be an effective treatment of pain associated with colic. in contrast to narcotic agents, its analgesic effects were not antagonized by naloxone, tolerance did not develop, and cross-tolerance to codeine did not occur. these results show that flunixin meglumine is an effective analgesic in animals, and drug dependence liability does not occur.

 

esting items

specifications

results

appearance

white to almost white, crystalline powder

conforms

solubility

freely soluble in water and methanol, paractically insoluble in acetone

conforms

identification 1

infrared absorption:197m;u ltraviolet absorption:197u

conforms

identification 2

water: free soluble;ethanol(96%):free soluble

ethyl acetate: practically insoluble

conforms

melting point

137~140℃

137.5~138.5

ph

5 %(w/v)water solution:7.0~9.0

8.2

related substances

2-chloropyridine-3carboxylic acid ≤0.2%

undetected

2-methyl-3-(trifluoromethyl)aniline ≤0.2%

undetected

ethyl 2-chloropyridine-3-carboxylate ≤0.2%

undetected

ethyl 2-[[2-methyl-3-(trifluoromethyl)

phenyl]amino]pyridine-3-carboxylate ≤0.2%

undetected

impurities

1. single impurity: not more than 0.2%

conforms

2. unknown impurity: not more than 0.2%

conforms

total impurities(1~2): not more than 0.5%

conforms

specific optical rotation

-9.0°~ -12.0°

-10.3°

solvent residue

isopropanol: not more than 0.5%

conforms

 

ethanol: not more than 0.5%

conforms

bacterial endotoxins

not more than 4.54 eu/mg

0.1 eu/mg

loss on drying

≤0.5%

0.2%

sulphated ash

≤0.1%

0.05%

residue on ignition

≤0.2%

0.1%

colour of solution

clear,less coloured than reference solution y6,b.p.(vet)

conforms

clarification

1.2g funixin meglumine/8.8g water

transparent

explanation

micronisarion 200±20um

assay (hplc)

99.0~101.0%

99.64%

conclusion

comply with usp 37/ep7/bpv2012

 

 

Article illustration
 

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.

 

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

 

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis. 

 

Think Chemistry,Think CHemWill

 

Article illustration

 

 

 

 

Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China


Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA


 

 

---any inquiries will be replied within 12 hours.

---golden manufactory under iso/gmp with large stock.

---dedication to quality,we have strict quality control system. 

---oem/odm available.

---sample is available for your evaluation & formulation development.

 
 
Website: http://www.chemwill.com

 

 

PLS contact

Ms Ella Lee  -   Deputy Sales Manager  

 
Phone: +86 -21-51086038
 
Email: chemwill_asia@126.com;chemwill@hotmail.com

Company Profile Introduction

Over 30 years experience in the chemical industry, Chemwill Asia Industrial co.,Ltd is one of the leading GMP complied manufacturer of Organic compounds in CHINA. Our main production base is located in Jiangsu province. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. Our advantageous business including: - Intermediate using for Pharmaceuticals - Active ingredient for Pharmaceutical and animal health (Human APIs and Veterinary APIs) - Fluorine, boronic acids, unnatural amino acids, cross linkers,chiral building blocks - Intermediate using for advanced performance materials - Monomer & polymers, high performance, photosensitive and specialty chemicals - Electro chemical materials(Lithium Battery, Photoresist, semiconductor, IT-related chemicals) * Custom synthesis from the laboratory scale to commercial production. * Contract research, custom manufacturing and contract-manufacture Ms Ella Lee - Deputy Sales Manager Phone: +86 -21-51086038 Email: chemwill_asia@126.com;chemwill@hotmail.com To learn more about our factory, PLS visit: www.chemwill.com

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