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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyrimidines>Chloropyrimidine>6-CHLORO-5-NITROPYRIMIDIN-4-AMINE
6-CHLORO-5-NITROPYRIMIDIN-4-AMINE
  • 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE
  • 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE
  • 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE

6-CHLORO-5-NITROPYRIMIDIN-4-AMINE NEW

Price Get Latest Price
Package 200kg
Min. Order: 100kg
Supply Ability: 20 tons
Update Time: 2025-04-02

Product Details

Product Name: 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE CAS No.: 4316-94-3
Min. Order: 100kg Purity: 0.99
Supply Ability: 20 tons Release date: 2025/04/02

4-Amino-5-Nitro-6-Chloropyrimidine CAS 4316-94-3 | Core Supplier of High-Activity Nitropyrimidine Intermediates


Product Basic Information

Chemical Name: 4-Amino-5-nitro-6-chloropyrimidine
CAS Number: 4316-94-3 (Highlighted as a Title-Level Keyword)
Molecular Formula: C4H3ClN4O2
Appearance: Pale Yellow to Yellow Crystalline Powder
Purity: ≥98.0% (HPLC, Pharmaceutical Intermediate Grade)

Key Physical and Chemical Properties (Structured Data Optimized)


PropertyParameter Value
Molecular Weight174.55 g/mol
Melting Point215-218°C (Decomposition)
Density (25°C)1.72 g/cm³
SolubilitySoluble in DMSO, DMF; Slightly soluble in Ethanol; Insoluble in Water
StabilityLight-sensitive, Stable at pH 4-9
Storage ConditionsSealed and Protected from Light, Store at -20°C in a Dry Place
Hygroscopicity≤0.5% (25°C/60% RH)


Upstream and Downstream Industry Chain Integration

▶ Upstream Raw Material Guarantee

  • Core Intermediates: 4,6-Dichloropyrimidine, Potassium Nitrate/Nitration Reagent

  • Process Optimization: Stepwise Nitration-Amination Technology (Overall Yield >80%, Impurities <0.5%)

▶ Downstream Application Expansion

  • Anticancer Drugs: Key Precursor for Thymidylate Synthase Inhibitors

  • Agricultural Fungicides: Modification of Molecular Skeleton of Pyrimidine Ester Compounds

  • Optoelectronic Materials: Synthesis of Organic Semiconductor Dopants

  • Molecular Probes: Development of DNA/RNA Base Analogues

Industry Solutions and Technical Advantages


Application AreaTypical ScenarioTechnical Advantages
Anticancer DrugsStructural Optimization of 5-Fluorouracil DerivativesAmino-Directed Acylation Yield >93% (HPLC Verified)
AgrochemicalsSynthesis of Methoxyacrylate FungicidesHydrolysis Resistance (Stability >90% at pH 5-8)
OLED MaterialsPreparation of Hole-Blocking Materials for Electron Transport LayersPurity ≥99.9% (Gradient Sublimation Process)
Chemical BiologyBase Modification Markers for Nucleic Acid DrugsNitro Reduction Reaction Selectivity >95%


SEO Keyword Matrix

Core Keyword Layout:

  • "4-Amino-5-nitro-6-chloropyrimidine Price"

  • "CAS 4316-94-3 Technical Parameters"

  • "High-Activity Nitropyrimidine Supplier"

Long-Tail Keyword Combinations:

  • "Custom Synthesis of Anticancer Drug Intermediates"

  • "Manufacturer of Raw Materials for Pyrimidine Ester Fungicides"

  • "Pharmaceutical Grade 4316-94-3 Producer"

Quality System and Service Commitment

✅ cGMP Compliant Production: Complies with ICH Q7 Standards for Active Pharmaceutical Ingredient Starting Materials
✅ Customized Services: Supports Orders from Gram to Hundred-Kilogram Levels (MOQ 50g)
✅ Analysis Report: Provides Full Documentation Including HPLC, 1H NMR, and Elemental Analysis
✅ Global Logistics: UN 3077 Certified Packaging (Moisture-Proof Aluminum Foil Bags + Desiccant)



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