RESATORVID

RESATORVID Basic information

Product Name:

RESATORVID

Synonyms:

RESATORVID;TAK 242;(6R)-6-[[(2-Chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid ethyl ester;TAK-242(Resatorvid);1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)aMino]sulfonyl]-, ethyl ester, (6R)-;Resatorvid(TAK-242);Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-, ethyl ester, (6R)-;(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate

CAS:

MF:

C15H17ClFNO4S

MW:

361.819

EINECS:

 

Product Categories:

MAPK

Mol File:

243984-11-4.mol

 

RESATORVID Chemical Properties

Melting point 

68-69℃

density 

1.39

 

Safety Information

MSDS Information

 

RESATORVID Usage And Synthesis

Uses

Resatorvid is a novel selective Toll-like receptor 4 signal transduction inhibitor. Resatorvid inhibits various kinds of inflammatory mediators such as nitric oxide (NO), tumor necrosis factor (TNF)-α , interleukin (IL)-1, IL-6, IL-10, macrophage inhibitory protein (MIP)-2 and prostaglandin E2 from lipopolysaccharide (LPS)-stimulated macrophages.

 

RESATORVID Preparation Products And Raw materials