Silibinin 22888-70-6

Silibinin COA TDS price MSDS

Silibinin MSDS

Silibinin TDS

Silibinin price

Product no. chemwill-Silibinin-920921

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Silibinin CAS 22888-70-6

2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin; Silymarin CAS 22888-70-6

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Name:    Silymarin

Milk thistle Silybinin and 80%silymarin
80% Silymarin 30% silybin+isosilybin

Name:    Silibinin
Synonyms:    silliver;silybine;silymarinei;silymaringroup;Silymrin;(2R,3R)-3,5,7-TRIHYDROXY-2-[(2R,3R)-3-(4-HYDROXY-3-METHOXY-PHENYL)-2-HYDROXYMETHYL-2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL]-CHROMAN-4-ONE;2-[2R,3R-DIHYDRO-3-(4-HYDROXY-3-METHOXYPHENYL)-2-(HYDROXYMETHYL)-1,4-BENZODIOXIN-6-YL]-2R,3R-DIHYDRO-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE;2,3-DIHYDRO-3-(4-HYDROXY-3-METHOXYPHENYL)-2-(HYDROXYMETHYL)-6-(3,5,7-TRIHYDROXY-4-OXOBENZOPYRAN-2-YL)BENZODIOXINE
CAS:    22888-70-6
MF:    C25H22O10
MW:    482.44
EINECS:    245-302-5
HS Code     29329990
 Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin, and others. Silibinin itself is mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. The mixture exhibits a number of pharmacological effects, particularly in the liver, and there is some clinical evidence for the use of silibinin as a supportive element in alcoholic and child grade 'A' liver cirrhosis.
silliver; Silibinin; SILYBIN A; silybine;
Appearance & Physical State     solid
Density     1.527g/cm3
Boiling Point     793ºC at 760mmHg
Melting Point     164-174ºC
Flash Point     274.5ºC
Refractive Index     1.684
Stability     Stable. Incompatible with strong oxidizing agents, strong bases.
Storage Condition     -20ºC
Vapor Pressure     1.63E-26mmHg at 25°C
Safety Info
RTECS     DJ2981770
Safety Statements     S26-S37/39
HS Code     2932999099
MSDS Information
Silibinin Usage And Synthesis
Chemical Properties    solid
Uses    Labelled Silybin (S465850). Hepatoprotectant.
Definition    ChEBI: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.
Silibinin Preparation Products And Raw materials
Product Categories:    Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical raw material;Plant extracts;chemical reagent;pharmaceutical intermediate;Flavanones;Natural Plant Extract;Angiogenesis InhibitorsCancer Research;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Plant extract;Inhibitors;-;Anti-proliferative AgentsNutrition Research;Angiogenesis;Biochemicals Found in Plants;Bioflavonoids;Cancer Research;Chemopreventive Agents;Aromatics;Chiral Reagents
Mol File:    22888-70-6.mol
Silibinin Structure
Silibinin Chemical Properties
Melting point     164-174°C
alpha     D20 +11° (c = 0.25 in acetone + alcohol)