![PD 0325901](https://img.chemicalbook.com/ProductImageEN/2019-8/Large/6d324105-7bd8-4447-99a0-f4f71bbea91b.png)
PD 0325901
Price | $3 |
Package | 1KG |
Min. Order: | 3KG |
Supply Ability: | 1kg,5kg,100kg |
Update Time: | 2019-08-27 |
Product Details
Product Name: PD 0325901 | CAS No.: 391210-10-9 |
Min. Order: 3KG | Purity: 98% |
Supply Ability: 1kg,5kg,100kg | Release date: 2019/08/27 |
Product Name:: Summer |
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Product Name:
PD 0325901
Synonyms:
InSolution MEK1/2 Inhibitor III, PD0325901 - CAS 391210-10-9 - Calbiochem;MEK1/2 Inhibitor III - CAS 391210-10-9 - Calbiochem;PD0325901 (PD325901);PD-0235901;N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]be;PD325901;N-[(R)-2,3 -Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylaMino)-benzaMide;N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide PD0325901
CAS:
391210-10-9
MF:
C16H14F3IN2O4
MW:
482.191
EINECS:
687-152-7
Product Categories:
-;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitor;Inhibitors;MAPK;API
Mol File:
391210-10-9.mol
![Article illustration](https://www.chemicalbook.com/CAS/GIF/391210-10-9.gif)
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PD 0325901 Chemical Properties
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Melting point
112-114°C
storage temp.
Store at -20°C
solubility
DMSO: soluble20mg/mL, clear
form
White to off-white solid
color
white to off-white
optical activity
[α]/D -1.8 to -3.5°, c = 1 mg/mL in methanol
InChIKey
SUDAHWBOROXANE-SECBINFHSA-N
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Safety Information
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Hazard Codes
T,N
Risk Statements
25-48-50
Safety Statements
22-36/37/39-61
RIDADR
UN 2811 6.1 / PGIII
WGK Germany
3
HazardClass
IRRITANT
HS Code
29242990
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MSDS Information
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PD 0325901 Usage And Synthesis
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Chemical Properties
White to Off-White Solid
Uses
The mitogenic extracellular kinase 1/2 (MEK1/2) inhibitor
Definition
ChEBI: A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).
Biological Activity
PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phosphorylation of ERK1 and ERK2.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
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sales@coreychem.com
sales@coreychem.com