ROSCOVITINE
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20kg |
| Update Time: | 2019-09-06 |
Product Details
| Product Name: ROSCOVITINE | CAS No.: 186692-46-6 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: 20kg | Release date: 2019/09/06 |
Abby043
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ROSCOVITINE Basic information
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Product Name:
ROSCOVITINE
Synonyms:
Roscovitine - CAS 186692-46-6 - Calbiochem;2-(R)-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;6-BENZYLAMINO-2-(R)-[(1-ETHYL)-2-HYDROXYETHYLAMINO]-9-ISOPROPYLPURINE;ROSCOVITINE;(R)-ROSCOVITINE;(R)-2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;P34 CDC2
CAS:
186692-46-6
MF:
C19H26N6O
MW:
354.45
EINECS:
Product Categories:
-;API intermediates;Apis;Inhibitors
Mol File:
186692-46-6.mol
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ROSCOVITINE Chemical Properties
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Melting point
106～107℃
density
1.3
storage temp.
−20°C
form
White to off-white solid
InChIKey
BTIHMVBBUGXLCJ-OAHLLOKOSA-N
CAS DataBase Reference
186692-46-6(CAS DataBase Reference)
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Safety Information
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Safety Statements
22-24/25
WGK Germany
3
HS Code
29335990
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MSDS Information
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SigmaAldrich
English
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ROSCOVITINE Usage And Synthesis
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Uses
Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.
Definition
ChEBI: 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.
Anticancer Research
Roscovitine a derivative of olomoucine which is isolated from Raphanus sativus isunder clinical trials (Shoeb 2006).
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
杨俊青
sales@coreychem.com
sales@coreychem.com