Side chain for meropenem
Price | $1 |
Package | 25Kg/Drum |
Min. Order: | 25Kg/Drum |
Supply Ability: | 1ton |
Update Time: | 2019-10-30 |
Product Details
Product Name: Side chain for meropenem | CAS No.: 96034-64-9 |
Min. Order: 25Kg/Drum | Purity: 99% |
Supply Ability: 1ton | Release date: 2019/10/30 |
Introduction
4r,5s,6s)-3-[[(3s,5s)-5-dimethylcarbamoylpyrrolidin-3-;(4r,5s,6s)
-3-[[(3s,5s)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2
-carboxylic acid;)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl
-7-oxo-,(4r-(3(s*,5s*),4-al;5-beta,6-beta(r*)))-ph;
C17H25N3O5S
Meropenem is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia. It is a beta-lactam and belongs to the subgroup of carbapenem, similar to imipenem and ertapenem.
Function
The spectrum of action includes many Gram-positive and Gram-negative bacteria (including Pseudomonas) and anaerobic bacteria. The overall spectrum is similar to that of imipenem, although meropenem is more active againstEnterobacteriaceae and less active against Gram-positive bacteria. It is also very resistant to extended-spectrum beta lactamases but may be more susceptible to metallo-beta-lactamases. Meropenem is frequently given in the treatment of febrile neutropenia. This condition frequently occurs in patients withhematological malignancies and cancer patients receiving anticancer drugs that cause bone marrow suppression. It is approved for complicated skin and skin structure infections, complicated intra-abdominal infections and bacterial meningitis.
Specification
Items
Specification
Results
Appearance
White or off-white powder
Conformed
Identification
Meets the requirements
Conformed
pH
7.3-8.3
8.07
Loss on drying
9.0%~12.0%
10.2%
Chromatographic
RRT(0.45)
0.80% MAX
0.13%
purity
RRT(1.90)
0.60% MAX
0.15%
Particulate matter
≥10 um
≤6000 pc/g
Conformed
≥25 um
≤600 pc/g
Conformed
Uniformity of dosage unites
Meets the requirements
conformed
Bacterial endotoxinsunder
≤0.125EU/mg
Conformed
Sterility
Meets the requirements
Conformed
Content of sodium
5.3%-8.0%
6.8%
Assay(C17H25N3O5S) on anhydrous basis
≥ 76.0%
80.7%
Conclusion
The product conforms the USP30 standard
Packing storage
In tight containers, the dry powder at controlled room temperature
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- Since: 2012-02-03
- Address: No. 7, No. 7, No. 1, No. 160, Qiaokou Road, Qiaokou District, Qiaokou city.