Clindamycin
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1IU |
| Supply Ability: | 100kg |
| Update Time: | 2019-12-25 |
Product Details
| Product Name: Clindamycin | CAS No.: 18323-44-9 |
| Min. Order: 1IU | Purity: 99% |
| Supply Ability: 100kg | Release date: 2019/12/25 |
| name: Cassie180 |
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Product Name:
Clindamycin
Synonyms:
Clindamycin (base and/or unspecified salts);(2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;CLDM;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4β-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;U-21251;Clindamycin Base;7-Chloro-7-deoxylincoMycin, 7-ChlorolincoMycin
CAS:
18323-44-9
MF:
C18H33ClN2O5S
MW:
424.98
EINECS:
242-209-1
Product Categories:
-;Inhibitors
Mol File:
18323-44-9.mol
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Clindamycin Chemical Properties
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alpha
D +214° (chloroform)
Boiling point
134°C (rough estimate)
density
1.1184 (rough estimate)
refractive index
1.6100 (estimate)
pka
7.6(at 25℃)
CAS DataBase Reference
18323-44-9(CAS DataBase Reference)
EPA Substance Registry System
L-threo-?-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- (18323-44-9)
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Safety Information
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Hazardous Substances Data
18323-44-9(Hazardous Substances Data)
Toxicity
LD50 subcutaneous in rat: 2618mg/kg
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MSDS Information
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Clindamycin Usage And Synthesis
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Uses
Clindamycin is a semi-synthetic analogue of lincomycin, prepared by chloride substitution of the exocyclic sugar hydroxy group. This affords a more hydrophobic compound with improved pharmacodynamics. Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin has been extensively studied with over 8,000 literature citations.
Definition
ChEBI: A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic.
Brand name
Cleocin (Pharmacia & Upjohn).
Contact allergens
This lincosanide antibiotic is used in topical form for acne, or systemically has been responsible for exanthematous rashes and acute generalized exanthematous pustulosis.
Veterinary Drugs and Treatments
Topical clindamycin is an optional topical treatment for feline acne.
Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosome; primary activity is against anaerobic and grampositive aerobic bacteria. For more information on the pharmacology of clindamycin, refer to the monograph for systemic use found in the main section.
Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosome; primary activity is against anaerobic and grampositive aerobic bacteria. For more information on the pharmacology of clindamycin, refer to the monograph for systemic use found in the main section.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
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