VIRGINIAMYCIN M1
| Price | $1 |
| Package | 1g |
| Min. Order: | 1g |
| Supply Ability: | g/kg/Ton |
| Update Time: | 2019-12-26 |
Product Details
| Product Name: VIRGINIAMYCIN M1 | CAS No.: 21411-53-0 |
| EC-No.: 244-376-6 | Min. Order: 1g |
| Purity: ≥98% | Supply Ability: g/kg/Ton |
| Release date: 2019/12/26 | |
| Delivery Time: Prompt | Packaging: Bottle/Durm/Bag |
| Transportation: By air/Bay Sea/Express |
Heidi 0729
Email:heidi@coreychem.com
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VIRGINIAMYCIN M1 Basic information
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Product Name:
VIRGINIAMYCIN M1
Synonyms:
MIKAMYCIN A;STAPHYLOMYCIN;VIRGINIAMYCINE;VIRGINIAMYCIN M1;C11299;MikamycinA, Staphylomycin;Antibiotic PA-114A1;Pristinamycin IIA
CAS:
21411-53-0
MF:
C28H35N3O7
MW:
525.59
EINECS:
244-376-6
Product Categories:
Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;antibiotic
Mol File:
21411-53-0.mol
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VIRGINIAMYCIN M1 Chemical Properties
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Melting point
165-167℃
alpha
D20 -218° ( c = 0.34 in ethanol)
Boiling point
825.2±65.0 °C(Predicted)
density
1.26±0.1 g/cm3(Predicted)
storage temp.
2-8°C
solubility
chloroform/methanol: soluble10mg/mL
pka
13.18±0.70(Predicted)
form
powder
color
yellow to tan
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Safety Information
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WGK Germany
3
HS Code
29419090
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MSDS Information
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Provider
Language
SigmaAldrich
English
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VIRGINIAMYCIN M1 Usage And Synthesis
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Chemical Properties
Light yellow powder
Uses
Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA.
Uses
Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginiamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA.
Uses
Macrolactone antibiotic. Antibacterial; growth promotant.
Definition
ChEBI: A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms includ ng methicillin-resistant Staphylococcus aureus.
Contact allergens
Pristinamycin is a systemic antibiotic of the synergistins/ streptogramins class, composed of two subunits: pristinamycin IA and pristinamycin IIA. It induces several types of drug reactions such as maculo-papular exanthema, systemic dermatitis, or acute generalized exanthematous pustulosis. Some patients have been previously skin-sensitized by virginiamycin. Crossreactivity is expected to virginiamycin and to the associated dalfopristin and quinupristin.
Contact allergens
Like the other streptogramin, pristinamycin, virginiamycin is made of two subunits, virginiamycin S1 and virginiamycin M1. Dermatitis was quite common in people using the formerly available topical virginiamycin. Occupational dermatitis was observed in the pharmaceutical industry, in breeders, and in a surgeon who used topical virginiamycin on postoperative wounds (personal observation).
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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