Nebivolol hydrochloride
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 1ton |
| Update Time: | 2020-01-01 |
Product Details
| Product Name: Nebivolol hydrochloride | CAS No.: 152520-56-4 |
| EC-No.: 200-258-5 | Min. Order: 1KG |
| Purity: 95-99% | Supply Ability: 1ton |
| Release date: 2020/01/01 | |
| contact : Flora@coreychem.com |
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Nebivolol hydrochloride Basic information
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Product Name:
Nebivolol hydrochloride
Synonyms:
a,a’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];(aR,a,2R,2)-rel-a,a[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];alpha,alpha'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol hydrochloride;D06622;Nebivolol hydrochloride (usan);(±)-[2R*(1S*5S*(S*))]-α,α'-[Iminobis(methylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol);Narbivolol;rel-(aR,a′R,2R,2′S)-a,a′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] hydrochloride
CAS:
152520-56-4
MF:
C22H26ClF2NO4
MW:
441.8959464
EINECS:
1806241-263-5
Product Categories:
Heterocycles;Intermediates & Fine Chemicals;-;Pharmaceuticals;API;R-67145
Mol File:
152520-56-4.mol
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Nebivolol hydrochloride Chemical Properties
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Melting point
220-222°C
storage temp.
Desiccate at RT
solubility
DMSO: ≥20mg/mL
form
powder
color
white to off-white
Merck
14,6432
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Safety Information
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Hazard Codes
Xn,N
Risk Statements
22-50/53
Safety Statements
60-61
RIDADR
3077
WGK Germany
3
HS Code
29322090
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MSDS Information
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Nebivolol hydrochloride Usage And Synthesis
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Chemical Properties
White to Off-White Powder
Uses
A ?-Adrenergic blocker. Used as an antihypertensive
Uses
Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM
Biological Activity
Highly selective β 1 -adrenoceptor antagonist (K i values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β 1 , 5-HT 1A , β 2 , 5-HT 2 , α 1 , H 1 and D 2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC 50 = 11.36 μ M in renal arteries) and displays antihypertensive activity in vivo .
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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