9-Methoxycamptothecin
| Price | $9.8 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20 tons |
| Update Time: | 2020-01-10 |
Product Details
| Product Name: 9-Methoxycamptothecin | CAS No.: 39026-92-1 |
| Min. Order: 1KG | Purity: ≥98% |
| Supply Ability: 20 tons | Release date: 2020/01/10 |
| Storage:: Keep away from heat， sparks and flames | Package:: Bottle / Drum / Bag |
| Delivery Time:: Prompt | Port:: Shanghai， Tianjin or Qingdao |
| Transportation:: By sea， express， air，railway | Product No. :: Jessie |
Jessie 0569
Contact : jessie@coreychem.com
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[Product Specification]
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Name
9-Methoxycamptothecin
Synonym
More Synonyms
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Description
9-Methoxycamptothecin (MCPT), isolated from Nothapodytes foetida, has antitumor activities through topoisomerase inhibition. 9-Methoxycamptothecin (MCPT) induces strong G2/M arrest and apoptosis in cancer[1][2].
Related Catalog
Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target
Topoisomerase[1]. Apoptosis[2].
References
[1]. Liao N, et al. 9-methoxycamptothecin from Nothapodytes foetida induces apoptosis in murine sarcoma S180 cells. Z Naturforsch C. 2011 Sep-Oct;66(9-10):471-6.
[2]. Wang H, et al. TNFα and Fas/FasL pathways are involved in 9-Methoxycamptothecin-induced apoptosis in cancer cells with oxidative stress and G2/M cell cycle arrest. Food Chem Toxicol. 2013 May;55:396-410.
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Density
1.5±0.1 g/cm3
Boiling Point
773.1±60.0 °C at 760 mmHg
Melting Point
223-225 ºC
Molecular Formula
C21H18N2O5
Molecular Weight
378.378
Flash Point
421.4±32.9 °C
Exact Mass
378.121582
PSA
90.65000
LogP
2.00
Vapour Pressure
0.0±2.8 mmHg at 25°C
Index of Refraction
1.723
Water Solubility
Slightly soluble (2.7 g/L) (25 ºC)
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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