8-Bromo-cGMP sodium NEW
| Price | $55 | $89 | $178 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-12 |
Product Details
| Product Name: 8-Bromo-cGMP sodium | CAS No.: 51116-01-9 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2024/11/12 |
Product Introduction
Bioactivity
| 名称 | 8-Bromo-cGMP sodium |
| 描述 | 8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimulated insulin release. |
| 体外活性 | 8-Bromo-cGMP sodium (1 µM-0.1 mM) can inhibit acetylcholine-induced increases in intracellular calcium concentrations.[1] 8-Bromo-cGMP sodium (1-100 μM; 16 h) induces the synthesis of HO-1 protein in a concentration-dependent fashion.[2] 8-Bromo-cGMP sodium (1-100 μM; 8 h) increases the resistance of LLC-PK1 cells to CsA toxicity in concentration-dependently.[2] |
| 体内活性 | 8-Bromo-cGMP sodium (0.3, 1, 3 nM; intrathecal administration; 10 min before the test; male ICR mice) significantly increases tail-flick latency in Vincristine-treated mice to the levels observed in vehicle-treated naive mice in a dose-dependent manner.[3] Additionally, 8-Bromo-cGMP sodium (10 mg/kg; iv; single dose) induces vasodilator responses in WT littermates and eNOS-Tg mice in the C57BL/6 background (19-35 g).[4] |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 90.0 mg/mL (201.8 mM), Sonication is recommended. |
| 关键字 | 8 Bromo cGMP sodium | 8-Bromo-cGMP sodium | 8BromocGMP sodium |
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| 相关库 | 经典已知活性库 | 疼痛相关化合物库 | 膜蛋白靶向化合物库 | 激酶抑制剂库 | 酪氨酸激酶分子库 | 神经保护化合物库 | 已知活性化合物库 | 离子通道库 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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