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Postion:Product Catalog >API>Nervous system drugs>Antidepressants, Antimanics drugs> Maprotiline Hydrochloride
	Maprotiline Hydrochloride
  • 	Maprotiline Hydrochloride

Maprotiline Hydrochloride

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 1ton
Update Time: 2020-01-13

Product Details

Product Name: Maprotiline Hydrochloride CAS No.: 10347-81-6
EC-No.: 200-258-5 Min. Order: 1g
Purity: 95-99% Supply Ability: 1ton
Release date: 2020/01/13
contact: Mary@coreychem.com
Common Name
Maprotiline Hydrochloride
CAS Number
10347-81-6
Molecular Weight
313.864
Density
N/A
Boiling Point
399.6ºC at 760 mmHg
Molecular Formula
C20H24ClN
Melting Point
230-232ºC
MSDS
ChineseUSA
Flash Point
187.7ºC
Symbol
Article illustration 
GHS07
Signal Word
Warning

 Use of Maprotiline Hydrochloride

 
Maprotiline HCl is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.Target: OthersMaprotiline (sold as Deprilept, Ludiomil, Psymion) is a tetracyclic antidepressant (TeCA). However, Maprotiline's fourth ring is spurious, as formed by a bridge across the central tricyclic ring. It is a strong norepinephrine reuptake inhibitor with only weak effects on serotonin and dopamine reuptake. It exerts strong blocking effect at H1 receptors, moderate at 5-HT2 and alpha1 and weak blocking effect at D2 and mACh postsynaptic receptors [1, 2].

 Names

Name
Maprotiline Hydrochloride
Synonym
More Synonyms

 Maprotiline Hydrochloride Biological Activity

Description
Maprotiline HCl is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.Target: OthersMaprotiline (sold as Deprilept, Ludiomil, Psymion) is a tetracyclic antidepressant (TeCA). However, Maprotiline's fourth ring is spurious, as formed by a bridge across the central tricyclic ring. It is a strong norepinephrine reuptake inhibitor with only weak effects on serotonin and dopamine reuptake. It exerts strong blocking effect at H1 receptors, moderate at 5-HT2 and alpha1 and weak blocking effect at D2 and mACh postsynaptic receptors [1, 2].
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References

[1]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8.

[2]. http://en.wikipedia.org/wiki/Maprotiline

 Chemical & Physical Properties

Boiling Point
399.6ºC at 760 mmHg
Melting Point
230-232ºC
Molecular Formula
C20H24ClN
Molecular Weight
313.864
Flash Point
187.7ºC
Exact Mass
313.159729
PSA
12.03000
LogP
5.40430
Vapour Pressure
9.8E-08mmHg at 25°C
Storage condition
Store at RT
Water Solubility
H2O: 50 mg/mL | Soluble to 50mg/ml in water. Soluble in ethanol at 10mM

 MSDS

Maprotiline Hydrochloride MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KJ4555000
CHEMICAL NAME :
9,10-Ethanoanthracene-9(10H)-propylamine, N-methyl-, hydrochloride
CAS REGISTRY NUMBER :
10347-81-6
LAST UPDATED :
199706
DATA ITEMS CITED :
31
MOLECULAR FORMULA :

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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