SPINOSAD
| Price | $1 |
| Package | 1g |
| Min. Order: | 1g |
| Supply Ability: | 200g |
| Update Time: | 2020-02-02 |
Product Details
| Product Name: SPINOSAD | CAS No.: 131929-60-7 |
| Min. Order: 1g | Purity: 99% |
| Supply Ability: 200g | Release date: 2020/02/02 |
Mary
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Product Name:
SPINOSAD
Synonyms:
1H-As-indaceno(3,2-D)oxacyclododecin-7,15-dione, 2-((6-deoxy-2,3,4-tri-o-methyl-alpha-L-mannopyranosyl)oxy)-13-(((2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-9-ethyl-2,3,3A,5A,5B,6,9,10,11,12,13,14,16A,16B-tetradecahydro-14-methyl-, (2R,3as,5ar,5bs,9S,13S,14R,16as,16br)-;1H-As-indaceno(3,2-D)oxacyclododecin-7,15-dione, 2,3,3A,5A,5B,6,9,10,11,12,13,14,16A,16B-tetradecahydro-2-((6-deoxy-2,3,4-tri-o-methyl-alpha-L-mannopyranosyl)oxy)- 13-((5-dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-9-ethyl-14-methyl-, (2R-(2R*,3as*,5ar*,5bs*,9S*,13S*(2R*,5S*,6R*),14R*,16as*,16br*))-;Ccris 8937;Hsdb 7006;Spinosyns;Lepicidin A, A 83543A, LY 232105;Spinosad A;Spinosyn A Solution, 1000ppm
CAS:
131929-60-7
MF:
C41H65NO10
MW:
731.96
EINECS:
620-162-1
Product Categories:
Mol File:
131929-60-7.mol
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SPINOSAD Chemical Properties
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Boiling point
801.5±65.0 °C(Predicted)
density
1.16±0.1 g/cm3(Predicted)
vapor pressure
Spinosyn A: 3.2 x 10-8 Pa
Spinosyn D: 2.1 x 10-8 Pa
Spinosyn D: 2.1 x 10-8 Pa
Water Solubility
Spinosyn A: 290 mg l-1 (pH 5); Spinosyn D: 29 mg l-1 (pH 5)
pka
Spinosyn A: 8.1 (base); Spinosyn D: 7.8 (base)
EPA Substance Registry System
Spinosyn A (131929-60-7)
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Safety Information
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RIDADR
3077
HazardClass
9
PackingGroup
III
Hazardous Substances Data
131929-60-7(Hazardous Substances Data)
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MSDS Information
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SPINOSAD Usage And Synthesis
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Uses
Spinosyn A is the major component of a complex of unusual, hydrophobic macrocyclic lactones isolated from Saccharopolyspora spinosa in 1991. The 12-membered macrocyclic lactone is fused to form a rare 12-5-6-5 tetracyclic ring system, with the macrocycle and the terminal cyclopentane bearing glycosides. Spinosyn A is a potent insecticide for crop pathogens and ectoparasite control on animals. The spinosyns have a unique mechanism of action involving disruption of nicotinic acetylcholine receptors.
Definition
ChEBI: A spinosyn in which the sugar amino and hydroxy groups are globally methylated. One of the two active ingredients of spinosad.
Veterinary Drugs and Treatments
For the prevention and treatment of fleas for one month on dogs 14 weeks of age and older.
Spinosad is a group 5 nicotinic acetylcholine receptor agonist, that causes involuntary muscle contractions and tremors secondary to motor neuron activation. Prolonged exposure causes paralysis and flea death. Flea death begins within 30 minutes of dosing and in 4 hours is complete. Spinosad does not interact with bindings sites of other insecticidal agents (GABA-ergic or nicotinic).
Spinosad is a group 5 nicotinic acetylcholine receptor agonist, that causes involuntary muscle contractions and tremors secondary to motor neuron activation. Prolonged exposure causes paralysis and flea death. Flea death begins within 30 minutes of dosing and in 4 hours is complete. Spinosad does not interact with bindings sites of other insecticidal agents (GABA-ergic or nicotinic).
Metabolic pathway
Spinosad consists of two major components, namely psinosyns A (ca 85%) and D (ca 15%). When either 14C-spinosyn A or -spinosyn D is applied in the soil under aerobic conditions, the major degradation product of spinosyn A is spinosyn B, resulting from demethylation on the forosamine sugar. Other degradation products are hydroxylation products of psinosyns A and B, probably on the aglycone portion of the molecule.
Degradation
Spinosad is relatively stable in water with no observed decomposition between pH 5 and 7. Measured DT50 values at pH 9 were 200 and 259 days, respectively, for spinosyns A and D (Saunders and Bret, 1997). Aqueous photolysis was very rapid with a DT50 of < 1 day in pH 7 buffered water at 25 °C (DowElanco, 1996). Spinosad was rapidly dissipated and degraded in an outdoor mesocosm study and on plant surfaces (Saunders and Bret, 1997).
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SPINOSAD Preparation Products And Raw materials
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Raw materials
D(+)-Glucose-->SOYBEAN OIL-->Dextrin-->Soy bean Isoflavone Isoflavone 10-40%-->Maltose-->CATION STANDARD - SODIUM-->D(+)-Xylose-->D-Mannitol -->HY SOY-->5 KG YEAST EXTRACT SERVABACTERPOWDER-->MILK-->Meat extracts, beef -->(Z)-9-Octadecenoic acid methyl ester-->D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE-->SOYBEAN MEAL-->beta-D-Fructopyranose-->D-Ribose-->ANION STANDARD - NITRATE-->RAFFINOSE-->N-Z-AMINE A-->SPINOSAD
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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