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Postion:Product Catalog >Garcinone D
Garcinone D
  • Garcinone D
  • Garcinone D
  • Garcinone D
  • Garcinone D
  • Garcinone D

Garcinone D

Price $9.8
Package 1KG
Min. Order: 1KG
Supply Ability: 20 tons
Update Time: 2020-02-07

Product Details

Product Name: Garcinone D CAS No.: 107390-08-9
Min. Order: 1KG Purity: >98%HPLC
Supply Ability: 20 tons Release date: 2020/02/07
Delivery Time:: Prompt Storage:: Keep away from heat, sparks and flames
Package:: Bottle / Drum / Bag Port:: Shanghai, Tianjin or Qingdao
Transportation:: By sea, express, air,railway No. :: Jessie

Jessie 785

Contact: jessie@coreychem.com

Welcome to contact us!

 

[Product Specification】

Names

Name
1,3,6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methylbut-2-enyl)xanthen-9-one
Synonym
More Synonyms

 Garcinone D Biological Activity

Description
Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners[1].
Related Catalog
Signaling Pathways >> Stem Cell/Wnt >> STAT
Signaling Pathways >> NF-κB >> Keap1-Nrf2
Signaling Pathways >> JAK/STAT Signaling >> STAT
Research Areas >> Neurological Disease
Target

p-STAT3

References

[1]. Yang X, et al. Garcinone D, a natural xanthone promotes C17.2 neural stem cell proliferation: Possible involvement of STAT3/Cyclin D1 pathway and Nrf2/HO-1 pathway. Neurosci Lett. 2016 Jul 28;626:6-12.

 Chemical & Physical Properties

Density
1.304
Boiling Point
674.2±55.0 °C at 760 mmHg
Melting Point
202-204 ºC
Molecular Formula
C24H28O7
Molecular Weight
428.475
Flash Point
231.2±25.0 °C
Exact Mass
428.183502
PSA
120.36000
LogP
3.71
Vapour Pressure
0.0±2.2 mmHg at 25°C
Index of Refraction
1.625
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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