![Citalopram hydrobromide](/ProductImageEN/2021-07/Large/4457beac-a942-432a-ab8c-8479281f0b35.jpg)
Citalopram hydrobromide NEW
Price | Get Latest Price | ||
Package | 1Kg/Bag | 25Kg/Bag | 100Kg/Bag |
Min. Order: | 1Kg/Bag |
Supply Ability: | 20 tons |
Update Time: | 2024-09-10 |
Product Details
Product Name: Citalopram hydrobromide | CAS No.: 59729-32-7 |
EC-No.: 261-890-6 | Min. Order: 1Kg/Bag |
Purity: 98.5% up / EP | Supply Ability: 20 tons |
Release date: 2024/09/10 |
Product Information
Poduct Name | Citalopram Hydrobromide,59729-32-7 |
Synonyms | Citalopram hydrobromide, 95%, selective serotonin reuptake inhibitor (SSRI) |
CAS No. | 59729-32-7 |
Molecular Formula | C20H22BrFN2O |
Molecular Weight | 405.3 |
EINECS No. | 261-890-6 |
Appearance | White to off-white crystalline powder |
Purity | 98%min |
Quality Standard | Enterprise standard |
Storage conditions | Store in a cool & dry place. Keep away from strong light and heat. |
Packing | 1kg/foil bag;25kg/drum |
Shipment | EMS;DHL;FedEx;TNT;UPS |
Delivery Time | 4-7 Working Days |
Payment Terms | T/T; Western Union; MoneyGram; Bitcoin |
Citalopram hydrobromate is a highly selective 5-hydroxytryptamine (5-HT) uptake inhibitor with antidepressant effects. The advantage of this drug is that it has no inhibitory effect on cholinergic muscarinic receptors, histamine receptors and α-adrenergic receptors. Because if these receptors are inhibited, many of the side effects of antidepressants can occur, such as dry mouth, sedation, and postural hypotension. Citalopram hydrobromide is equally effective in patients with both endogenous and non-endogenous depression, and its antidepressant effects are usually established after 2-4 weeks. Citalopram hydrobromide does not affect the cardiac conduction system or blood pressure, which is particularly important in elderly patients. In addition, citalopram hydrobromide does not affect the blood, liver and kidney systems. The rare side effects and mild sedative nature make it especially suitable for long-term treatment. Neither causes weight gain nor reinforces the effects of alcohol.
Usage
Citalopram Hydrobromide is used for depressive disorders (endogenous and non-endogenous depression), severe patients
have significant or persistent depression or restlessness (lasting for at least 2 weeks), mainly including the following symptoms:
depression, loss of interest, significant changes in weight or appetite, insomnia or lethargy, psychomotor excitement or retardation,
excessive fatigue, guilt or inferiority, slow thinking or inattention. Suicide attempts or ideas. It is also used for depression associated with physical diseases, such as post-stroke depression. It can also be used as an adjuvant for the treatment of anxiety disorder, panic disorder, and chronic pain.
Dosage of Citalopram Hydrobromide Powder
Oral: Adults once a day. The initial dose is 20 mg per day, which can be increased to 40-60 mg per day if a clinical need arises.
The dosage of patients over 65 years old was reduced by half (10-30 mg per day). Antidepressant treatment must last for an
appropriate period of time. It takes 4 to 6 months for the manic-depressive disorder. If insomnia or severe inability to sit still occurs,
sedatives should be supplemented in the acute phase. Children's clinical experience is unknown, please follow the doctor's advice.
Drug Interaction of Citalopram Hydrobromide Powder
The Patients who taking monoamine oxidase inhibitors should not use citalopram hydrobromide at the same time. Citalopram
hydrobromide can be used after 14 days of discontinuation of the monoamine oxidase inhibitor. However, if a reversible
monoamine oxidase inhibitor with a short half-life, such as moclobemide, is used, citalopram hydrobromide can be used after
one day of withdrawal.
Side Effect of Citalopram Hydrobromide Powder
Citalopram Hydrobromide's Side effects are usually rare, mild, and transient. The most common adverse reactions were nausea,
increased sweating, reduced salivation, headache, and shortened sleep time. It is usually evident in the first or second week of
treatment and generally disappears as depression improves. Epilepsy seizures have been observed in rare cases. In patients
with bradycardia, bradycardia can make treatment more complex.
COA
ITEMS | SPECIFICATION | TEST RESULTS |
Appearance | Off-white or white powder | Conforms |
Identification | HPLC, NMR; LC-MS | Conforms |
Related substances | Individual impurity≤0.5% | 0.09% |
Total impurities≤1.0% | 0.20% | |
Loss on drying | ≤0.5% | 0.3% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤10ppm | Conforms |
Assay | ≥98.0 % | 99.1% |
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- Since: 1996-07-16
- Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.