Doxorubicin hydrochloride NEW

Doxorubicin Hydrochloride CAS25316-40-9 Factory Supply Directly Antitumor Antibiotic

1. CAS 25316-40-9

2. Product Name: Doxorubicin Hydrochloride

3. Storage 2-8°C

4. Purity: 99%

5. Synonyms: ADRIACIN;ADRIBLASTINA;ADRIBLASTINA HYDROCHLORIDE;ADRIAMYCIN HCL;ADRIAMYCIN HYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9, 10-tetra hydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride;14-HYDROXYDAUNOMYCIN HCL;14-HYDROXYDAUNOMYCIN HYDROCHLORIDE

6. Type: Chemical Reagent

7. Function: Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently. And it is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.

Definition ChEBI: Doxorubicin hydrochloride is an anthracycline.

8. HS Code: 29419090

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