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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antiviral drugs>Adefovir
Adefovir
  • Adefovir
  • Adefovir
  • Adefovir
  • Adefovir
  • Adefovir

Adefovir

Price Get Latest Price
Package 1KG 25KG 100KG
Min. Order: 1KG
Supply Ability: 20TONS
Update Time: 2024-09-30

Product Details

Product Name: Adefovir CAS No.: 106941-25-7
Min. Order: 1KG Purity: 99%
Supply Ability: 20TONS Release date: 2024/09/30

Product Description


 

Product nameAdefovir
CAS106941-25-7
Appearancewhite powder
Assay99%
StorageCool and Protect from light





Adefovir
Product Name Adefovir

CAS 106941-25-7

MF C8H12N5O4P

MW 273.19

EINECS 600-789-7

MOL File106941-25-7.mol

Chemical Properties

Melting point >260°C
Boiling point 632.5±65.0 °C(Predicted)
Density  1.88
storage temp.  -20°C
solubility  0.1 M NaOH: ≥5mg/mL
pka pKa1 2.0, pKa2 6.8(at 25ºC)
form  powder
color  white to beige
InChIKey SUPKOOSCJHTBAH-UHFFFAOYSA-N
CAS DataBase Reference 106941-25-7(CAS DataBase Reference)



Usage And Synthesis
Description

Adefovir (Trade name: Preveon, Hepsera) is a prescription drug used for the treatment of chronic infections of hepatitis B virus. It can be formulated as the pivoxil prodrug adefovir dipivoxil. However, it shows no effect against HIV-1. As a orally administrated acyclic nucleotide analog reverse transcriptase inhibitor, it blocking the reproduction of HBV through inhibiting the reverse transcriptase in the body. One of its advantages over another anti-HBV drug, lamivudine is that it is much harder for the virus to develop resistance to it.

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Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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