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Postion:Product Catalog >AMPK-IN-3
AMPK-IN-3
  • AMPK-IN-3

AMPK-IN-3 NEW

Price $109 $263 $422
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: AMPK-IN-3 CAS No.: 2417674-27-0
Purity: 99.13% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAMPK-IN-3
DescriptionAMPK-IN-3 is a novel, selective and potent AMPK inhibitor with inhibitory effects on AMPK (α2), AMPK (α1) and KDR, with IC50 values of 60.7, 107 and 3820 nM, respectively.AMPK-IN-3 showed anticancer activity in K562 cells.
In vitroAt a concentration of 100 nM, AMPK-IN-3 exhibits inhibition values of 64%, 43%, 41%, and 29% for AMPK(α2), FLT1, JAK1 JH2-pseudokinase, and AMPK(α1), respectively[1].In K562 cells, AMPK-IN-3, when applied at concentrations of 0.195313, 0.78125, 3.125, 12.5, and 50 µM for 2 hours, reduces the level of p-ACC[1]. For a duration of 24, 48, and 72 hours, AMPK-IN-3, within the concentration range of 1-100 µM, demonstrates potent inhibition of cellular AMPK activity without affecting cell viability[1].
StorageShipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (110.73 mM), Sonication is recommended.
Inhibitors RelatedSorafenib | Metformin hydrochloride | Chitosan oligosaccharide
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Epigenetics Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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