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Postion:Product Catalog >Antitumor agent-19
Antitumor agent-19
  • Antitumor agent-19

Antitumor agent-19 NEW

Price $117 $175 $268
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Antitumor agent-19 CAS No.: 2379727-90-7
Purity: 99% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAntitumor agent-19
DescriptionAntitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.
In vitroIn RAW 264.7 cells, Antitumor agent-19 (10 µM, 20 µM, or 50 µM) effectively and dose-dependently induces the expression of M1-phenotype macrophage markers including IL-1β, TNF-α, iNOS and IL-12α. Antitumor agent-19 dose-dependently repolarizes tumor-associated macrophages from M1 (anti-tumor) and M2 (pro-tumor)[1].
In vivoIn C57BL/6 female mice with lewis lung cancer cells, Antitumor agent-19 (5 mg/kg; i.p.) remarkably inhibits tumor growth. The synergy of Antitumor agent-19 with anti-PD-1 antibody shows more superior antineoplastic effects in vivo[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (102.48 mM)
KeywordsAntitumor agent-19 | Antitumor agent19 | Antitumor agent 19
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hills
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