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Postion:Product Catalog >APY29
APY29
  • APY29

APY29 NEW

Price $36 $59 $97
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: APY29 CAS No.: 1216665-49-4
Purity: 98.46% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAPY29
DescriptionAPY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
In vitroAPY29 selectively influences IRE1α by divergently modulating its RNase activity and oligomerization state through the same binding site, showing opposing effects on RNase activity. Additionally, APY29 has a dose-dependent, contrasting impact on ER stress-induced activation of the endogenous IRE1α RNase [1].
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 12.5 mg/mL (37.61 mM), Sonication is recommended.
H2O : Insoluble
KeywordsIRE1 | Inositol requiring enzyme 1 | Inhibitor | inhibit | APY-29 | APY29 | APY 29
Inhibitors RelatedB I09 | Sunitinib | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde | Sunitinib Malate | D-F07 | STF-083010 | MKC8866 | GSK2850163 (S enantiomer) | 4μ8C | GSK2850163 | Toyocamycin | IXA4
Related Compound LibrariesTarget-Focused Phenotypic Screening Library | Bioactive Compound Library | Endoplasmic Reticulum Stress Compound Library | Kinase Inhibitor Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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