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Postion:Product Catalog >Biochemical Engineering>Nucleoside drugs>Nucleotides and their analogs>Azacitidine
Azacitidine
  • Azacitidine

Azacitidine NEW

Price Get Latest Price
Package 1g
Min. Order: 1g
Supply Ability: 100kg
Update Time: 2024-03-12

Product Details

Product Name: Azacitidine CAS No.: 320-67-2
Min. Order: 1g Purity: 98% HPLC
Supply Ability: 100kg Release date: 2024/03/12

Azacitidine is a cytidine nucleoside analog that produces antitumor effects by causing DNA demethylation and direct cytotoxicity to abnormal hematopoietic cells in the bone marrow. The concentration at which azacitidine has the maximum inhibitory effect on DNA methylation in vitro has no obvious inhibitory effect on DNA synthesis. Demethylation of DNA restores the normal function of genes, which is critical for cell differentiation and proliferation. The cytotoxic effects of azacitidine cause the death of rapidly dividing cells, including cancer cells that do not respond to normal growth regulatory mechanisms. Cells in the non-proliferative phase are relatively insensitive to azacitidine. It can be used to treat intermediate-2/high-risk myelodysplastic syndrome, acute myeloid leukemia (AML) with 20-30% bone marrow blasts, and chronic myelomonocytic leukemia (CMML). It also has certain curative effect on breast cancer, intestinal cancer and melanoma.

This drug reduces the growth of cancer cells and suppresses the immune system. It is used to treat myeloid dyspoietic syndrome and certain types of leukemia.

Company Profile Introduction

Shandong Perfect Biotechnology Co.Ltd founded in 2014, the company is a supplier and service provider of pharmaceutical and chemical raw materials and animal husbandry and animal health industries. The company is located in Jinan, a beautiful spring city, where the transportation is developed, the logistics is convenient, and the industrial supporting resources are abundant, which provides a stable foundation for the promotion of the company's products. In 2018, the company initiated the establishment of Shandong Qinshi Biotechnology Co., Ltd. to serve domestic veterinary drug preparation companies, and Qinshi successfully passed the national veterinary drug GSP certification on September 10, 2018. In 2020, the company passed the ISO quality management system certification. As a result, the company has formed a pattern in which Jihao Company exports pharmaceutical and chemical raw materials and intermediates, and Qinshi Company serves domestic animal protection enterprises as veterinary raw materials. In this way, it can be more stable and standardized to meet the needs of different customers at home and abroad. At present, the company cooperates closely with several university research institutes and high-tech pharmaceutical industry companies, strictly controls each link from product research and development, production, sales, and dares to innovate, and continuously improves product quality and competitive advantages to promote the company's benign and stable development. We continue to develop superior varieties with our partners, and provide customers with products that meet customer requirements in accordance with CP, JP, BP, USP, EP and other standards, making our products and services a close and stable partner for customers. The company pays equal attention to the development of both international and domestic markets, and a complete sales team can serve its partners wholeheartedly. We provide products and services to our customer

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  • Since: 2014-09-09
  • Address: No.28 Hua Long Road,Ji Nan City,China
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