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B7-33 (6mg)

Size: 6mg
Contents: B7-33 (6mg)
Form: Lyophilized powder
Purity: >99%

B7-33 Peptide

H2-relaxin is a naturally occurring protein and the synthetic analog of this protein is the B7-33 peptide. Considered to be structurally similar to H2-relaxin, B7-33 may possess anti-fibrotic potential.

The H2-relaxin protein is a protein class comprised of relaxin, H3-relaxin, insulin-like peptide-3, and insulin-like peptide-5. All these proteins have been suggested to exhibit a variety of biological actions, including possibly affecting genetic functions and the reproductive, musculoskeletal, and cardiovascular systems. (2)

There are four different receptors that these naturally produced relaxin proteins are considered to be binding agents with, namely RXFP-1, RXFP-2, RXFP-3 and RXFP-4. Each receptor has a different action, as outlined below (2):

• RXFP-1 receptor is suggested to influence sperm movement, improve joint health and play a role in pregnancy.

• RXFP-2 receptor appears to affect the process of testicular descent.

• RXFP-3 receptor may play a role in sleep disturbances.

• RXFP-4 receptor has shown signs of affecting hunger cycles.

Due to the variety of receptors involved and such a wide range of biological impact, extensive research has been conducted on the relaxin protein and its analogues, such as B7-33 peptide, to fully understand their potential.