Berberine sulfate NEW
| Price | $39 | $51 | $68 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Berberine sulfate | CAS No.: 316-41-6 |
| Purity: 99.48% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Berberine sulfate |
| Description | Berberine sulfate (Berberal) is a quaternary ammonium salt of the benzylisoquinoline alkaloid proto-berberines, which can be used in the study of type 2 diabetes mellitus, abdominal obesity and metabolism-related fatty liver disease. |
| In vitro | Berberine sulfate (1.25-160 μM; 72 h) has a potential inhibitory effect on the proliferation of four colorectal cancer cell lines, LoVo, HCT116, SW480, and HT-29.[5] Berberine suLfate (1.25-160 μM; 24-72 h) induces time- and dose-dependent inhibition of LoVo cell growth.[5] LoVo cells were exposed to Berberine sulfate (10 -80 μM) for 24 hours. Cell cycle analysis of LoVo cells treated with 40 μM berberine by flow cytometry showed an accumulation of cells in the G2/M phase.[5] Berberine sulfate (10 -80 μM) inhibits the expression of cyclin B1, cdc2, and cdc25c proteins after 24 hours, especially at the dose of 80.0 μM.[5] |
| In vivo | Berberine sulfate (10, 30, or 50 mg/kg/day; gastrointestinal gavage; 10 consecutive days) inhibits the growth of human colorectal adenocarcinoma in vivo. Berberine (30 and 50 mg/kg/d; gastrointestinal gavage) inhibited the growth of human colorectal adenocarcinoma xenografts in nude mice by 33.1% and 45.3%, respectively.[5] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 7.69 mg/mL (10 mM), Sonication is recommended. H2O : 38.46 mg/mL (50.03 mM), Sonication is recommended. |
| Keywords | Berberine Sulfate | Berberin Sulfate |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Alkaloid Natural Product Library | Drug Repurposing Compound Library | Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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